Gene expression profiling of fibroblasts in a family with LMNA-related cardiomyopathy reveals molecular pathways implicated in disease pathogenesis

BACKGROUND: Intermediate filament proteins that construct the nuclear lamina of a cell include the Lamin A/C proteins encoded by the LMNA gene, and are implicated in fundamental processes such as nuclear structure, gene expression, and signal transduction. LMNA mutations predominantly affect mesoder...

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Detalles Bibliográficos
Autores principales: Widyastuti, Halida P., Norden-Krichmar, Trina M., Grosberg, Anna, Zaragoza, Michael V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7374820/
https://www.ncbi.nlm.nih.gov/pubmed/32698886
http://dx.doi.org/10.1186/s12881-020-01088-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7374820/
https://www.ncbi.nlm.nih.gov/pubmed/32698886
http://dx.doi.org/10.1186/s12881-020-01088-w

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