Cargando…
A substrate‐based ontology for human solute carriers
Solute carriers (SLCs) are the largest family of transmembrane transporters in the human genome with more than 400 members. Despite the fact that SLCs mediate critical biological functions and several are important pharmacological targets, a large proportion of them is poorly characterized and prese...
Autores principales: | Meixner, Eva, Goldmann, Ulrich, Sedlyarov, Vitaly, Scorzoni, Stefania, Rebsamen, Manuele, Girardi, Enrico, Superti‐Furga, Giulio |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7374931/ https://www.ncbi.nlm.nih.gov/pubmed/32697042 http://dx.doi.org/10.15252/msb.20209652 |
Ejemplares similares
-
Gain-of-function genetic screens in human cells identify SLC transporters overcoming environmental nutrient restrictions
por: Rebsamen, Manuele, et al.
Publicado: (2022) -
SLC38A9: A lysosomal amino acid transporter at the core of the amino acid-sensing machinery that controls MTORC1
por: Rebsamen, Manuele, et al.
Publicado: (2015) -
The Bicarbonate Transporter SLC4A7 Plays a Key Role in Macrophage Phagosome Acidification
por: Sedlyarov, Vitaly, et al.
Publicado: (2018) -
Epistasis-driven identification of SLC25A51 as a regulator of human mitochondrial NAD import
por: Girardi, Enrico, et al.
Publicado: (2020) -
Detection of Chemical Engagement of Solute Carrier
Proteins by a Cellular Thermal Shift Assay
por: Hashimoto, Mari, et al.
Publicado: (2018)