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Incorporation of T-cell epitopes from tetanus and diphtheria toxoids into in-silico-designed hypoallergenic vaccine may enhance the protective immune response against allergens

OBJECTIVE(S): New generation of allergy vaccines is capable of promoting the development of protective IgG and blocking the functionality of allergen-specific IgE. We incorporated universal and powerful T-cell epitopes from tetanus and diphtheria toxoids (TD epitope) into recombinant Che a 2, the we...

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Detalles Bibliográficos
Autores principales:	Ghasemi, Ali, Falak, Reza, Mohammadi, Mohsen, June Maleki, Soheila, Assarezadegan, Mohamad-Ali, Jafary, Mojtaba
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Mashhad University of Medical Sciences 2020
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7374995/ https://www.ncbi.nlm.nih.gov/pubmed/32742602 http://dx.doi.org/10.22038/ijbms.2020.39749.9422

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