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Prevalence of admission plasma glucose in 'diabetes' or 'at risk' ranges in hospital emergencies with no prior diagnosis of diabetes by gender, age and ethnicity

AIMS: To establish the prevalence of admission plasma glucose in 'diabetes' and 'at risk' ranges in emergency hospital admissions with no prior diagnosis of diabetes; characteristics of people with hyperglycaemia; and factors influencing glucose measurement. METHODS: Electronic p...

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Autores principales: Ghosh, Sandip, Manley, Susan E., Nightingale, Peter G., Williams, John A., Susarla, Radhika, Alonso‐Perez, Irene, Stratton, Irene M., Gkoutos, Georgios V., Webber, Jonathan, Luzio, Stephen D., Hanif, Wasim, Roberts, Graham A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7375073/
https://www.ncbi.nlm.nih.gov/pubmed/32704561
http://dx.doi.org/10.1002/edm2.140
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author Ghosh, Sandip
Manley, Susan E.
Nightingale, Peter G.
Williams, John A.
Susarla, Radhika
Alonso‐Perez, Irene
Stratton, Irene M.
Gkoutos, Georgios V.
Webber, Jonathan
Luzio, Stephen D.
Hanif, Wasim
Roberts, Graham A.
author_facet Ghosh, Sandip
Manley, Susan E.
Nightingale, Peter G.
Williams, John A.
Susarla, Radhika
Alonso‐Perez, Irene
Stratton, Irene M.
Gkoutos, Georgios V.
Webber, Jonathan
Luzio, Stephen D.
Hanif, Wasim
Roberts, Graham A.
author_sort Ghosh, Sandip
collection PubMed
description AIMS: To establish the prevalence of admission plasma glucose in 'diabetes' and 'at risk' ranges in emergency hospital admissions with no prior diagnosis of diabetes; characteristics of people with hyperglycaemia; and factors influencing glucose measurement. METHODS: Electronic patient records for 113 097 hospital admissions over 1 year from 2014 to 2015 included 43 201 emergencies with glucose available for 31 927 (74%) admissions, comprising 22 045 people. Data are presented for 18 965 people with no prior diagnosis of diabetes and glucose available on first attendance. RESULTS: Three quarters (14 214) were White Europeans aged 62 (43‐78) years, median (IQ range); 12% (2241) South Asians 46 (32‐64) years; 9% (1726) Unknown/Other ethnicities 43 (29‐61) years; and 4% (784) Afro‐Caribbeans 49 (33‐63) years, P < .001. Overall, 5% (1003) had glucose in the 'diabetes' range (≥11.1 mmol/L) higher at 8% (175) for South Asians; 16% (3042) were ‘at risk’ (7.8‐11.0 mmol/L), that is 17% (2379) White Europeans, 15% (338) South Asians, 14% (236) Unknown/Others and 11% (89) Afro‐Caribbeans, P < .001. The prevalence for South Asians aged <30 years was 2.1% and 5.2%, respectively, 2.6% and 8.6% for Afro‐Caribbeans <30 years, and 2.0% and 8.4% for White Europeans <40 years. Glucose increased with age and was more often in the 'diabetes' range for South Asians than White Europeans with South Asian men particularly affected. One third of all emergency admissions were for <24 hours with 58% of these having glucose measured compared to 82% with duration >24 hours. CONCLUSIONS: Hyperglycaemia was evident in 21% of adults admitted as an emergency; various aspects related to follow‐up and initial testing, age and ethnicity need to be considered by professional bodies addressing undiagnosed diabetes in hospital admissions.
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spelling pubmed-73750732020-07-22 Prevalence of admission plasma glucose in 'diabetes' or 'at risk' ranges in hospital emergencies with no prior diagnosis of diabetes by gender, age and ethnicity Ghosh, Sandip Manley, Susan E. Nightingale, Peter G. Williams, John A. Susarla, Radhika Alonso‐Perez, Irene Stratton, Irene M. Gkoutos, Georgios V. Webber, Jonathan Luzio, Stephen D. Hanif, Wasim Roberts, Graham A. Endocrinol Diabetes Metab Original Research Articles AIMS: To establish the prevalence of admission plasma glucose in 'diabetes' and 'at risk' ranges in emergency hospital admissions with no prior diagnosis of diabetes; characteristics of people with hyperglycaemia; and factors influencing glucose measurement. METHODS: Electronic patient records for 113 097 hospital admissions over 1 year from 2014 to 2015 included 43 201 emergencies with glucose available for 31 927 (74%) admissions, comprising 22 045 people. Data are presented for 18 965 people with no prior diagnosis of diabetes and glucose available on first attendance. RESULTS: Three quarters (14 214) were White Europeans aged 62 (43‐78) years, median (IQ range); 12% (2241) South Asians 46 (32‐64) years; 9% (1726) Unknown/Other ethnicities 43 (29‐61) years; and 4% (784) Afro‐Caribbeans 49 (33‐63) years, P < .001. Overall, 5% (1003) had glucose in the 'diabetes' range (≥11.1 mmol/L) higher at 8% (175) for South Asians; 16% (3042) were ‘at risk’ (7.8‐11.0 mmol/L), that is 17% (2379) White Europeans, 15% (338) South Asians, 14% (236) Unknown/Others and 11% (89) Afro‐Caribbeans, P < .001. The prevalence for South Asians aged <30 years was 2.1% and 5.2%, respectively, 2.6% and 8.6% for Afro‐Caribbeans <30 years, and 2.0% and 8.4% for White Europeans <40 years. Glucose increased with age and was more often in the 'diabetes' range for South Asians than White Europeans with South Asian men particularly affected. One third of all emergency admissions were for <24 hours with 58% of these having glucose measured compared to 82% with duration >24 hours. CONCLUSIONS: Hyperglycaemia was evident in 21% of adults admitted as an emergency; various aspects related to follow‐up and initial testing, age and ethnicity need to be considered by professional bodies addressing undiagnosed diabetes in hospital admissions. John Wiley and Sons Inc. 2020-05-15 /pmc/articles/PMC7375073/ /pubmed/32704561 http://dx.doi.org/10.1002/edm2.140 Text en © 2020 The Authors. Endocrinology, Diabetes & Metabolism published by John Wiley & Sons Ltd. This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Research Articles
Ghosh, Sandip
Manley, Susan E.
Nightingale, Peter G.
Williams, John A.
Susarla, Radhika
Alonso‐Perez, Irene
Stratton, Irene M.
Gkoutos, Georgios V.
Webber, Jonathan
Luzio, Stephen D.
Hanif, Wasim
Roberts, Graham A.
Prevalence of admission plasma glucose in 'diabetes' or 'at risk' ranges in hospital emergencies with no prior diagnosis of diabetes by gender, age and ethnicity
title Prevalence of admission plasma glucose in 'diabetes' or 'at risk' ranges in hospital emergencies with no prior diagnosis of diabetes by gender, age and ethnicity
title_full Prevalence of admission plasma glucose in 'diabetes' or 'at risk' ranges in hospital emergencies with no prior diagnosis of diabetes by gender, age and ethnicity
title_fullStr Prevalence of admission plasma glucose in 'diabetes' or 'at risk' ranges in hospital emergencies with no prior diagnosis of diabetes by gender, age and ethnicity
title_full_unstemmed Prevalence of admission plasma glucose in 'diabetes' or 'at risk' ranges in hospital emergencies with no prior diagnosis of diabetes by gender, age and ethnicity
title_short Prevalence of admission plasma glucose in 'diabetes' or 'at risk' ranges in hospital emergencies with no prior diagnosis of diabetes by gender, age and ethnicity
title_sort prevalence of admission plasma glucose in 'diabetes' or 'at risk' ranges in hospital emergencies with no prior diagnosis of diabetes by gender, age and ethnicity
topic Original Research Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7375073/
https://www.ncbi.nlm.nih.gov/pubmed/32704561
http://dx.doi.org/10.1002/edm2.140
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