Alzheimer's amyloid‐β and tau protein accumulation is associated with decreased expression of the LDL receptor‐associated protein in human brain tissue

INTRODUCTION: One of the major neuropathological features of Alzheimer's disease (AD) is the accumulation of amyloid‐β (Aβ) protein in the brain. Evidence suggests that the low‐density lipoprotein receptor‐associated protein (RAP) binds strongly to Aβ and enhances its cellular uptake and that d...

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Detalles Bibliográficos
Autores principales: Shepherd, Claire E., Affleck, Andrew J., Bahar, Anita Y., Carew‐Jones, Francine, Gregory, Gillian, Small, David H., Halliday, Glenda M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7375106/
https://www.ncbi.nlm.nih.gov/pubmed/32484608
http://dx.doi.org/10.1002/brb3.1672

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7375106/
https://www.ncbi.nlm.nih.gov/pubmed/32484608
http://dx.doi.org/10.1002/brb3.1672

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