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Alzheimer's amyloid‐β and tau protein accumulation is associated with decreased expression of the LDL receptor‐associated protein in human brain tissue
INTRODUCTION: One of the major neuropathological features of Alzheimer's disease (AD) is the accumulation of amyloid‐β (Aβ) protein in the brain. Evidence suggests that the low‐density lipoprotein receptor‐associated protein (RAP) binds strongly to Aβ and enhances its cellular uptake and that d...
Autores principales: | Shepherd, Claire E., Affleck, Andrew J., Bahar, Anita Y., Carew‐Jones, Francine, Gregory, Gillian, Small, David H., Halliday, Glenda M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7375106/ https://www.ncbi.nlm.nih.gov/pubmed/32484608 http://dx.doi.org/10.1002/brb3.1672 |
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