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Hypoxic preconditioning enhances the differentiation of bone marrow stromal cells into mature oligodendrocytes via the mTOR/HIF‐1α/VEGF pathway in traumatic brain injury

OBJECTIVE: Traumatic brain injury (TBI) results not only in gray matter damage, but also in severe white matter injury (WMI). Previous findings support hypoxic preconditioning (HP) could augment the efficacy of bone marrow stromal cell (BMSC) transplantation in a TBI mouse model. However, whether HP...

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Detalles Bibliográficos
Autores principales: Yuan, Xiaoyu, Luo, Qianqian, Shen, Lihua, Chen, Jin, Gan, Deqiang, Sun, Yechao, Ding, Lingzhi, Wang, Guohua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7375110/
https://www.ncbi.nlm.nih.gov/pubmed/32475084
http://dx.doi.org/10.1002/brb3.1675