Cargando…

Hypoxic preconditioning enhances the differentiation of bone marrow stromal cells into mature oligodendrocytes via the mTOR/HIF‐1α/VEGF pathway in traumatic brain injury

OBJECTIVE: Traumatic brain injury (TBI) results not only in gray matter damage, but also in severe white matter injury (WMI). Previous findings support hypoxic preconditioning (HP) could augment the efficacy of bone marrow stromal cell (BMSC) transplantation in a TBI mouse model. However, whether HP...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yuan, Xiaoyu, Luo, Qianqian, Shen, Lihua, Chen, Jin, Gan, Deqiang, Sun, Yechao, Ding, Lingzhi, Wang, Guohua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2020
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7375110/ https://www.ncbi.nlm.nih.gov/pubmed/32475084 http://dx.doi.org/10.1002/brb3.1675

Ejemplares similares

Hypoxia preconditioning protection of corneal stromal cells requires HIF1α but not VEGF
por: Xing, Dongmei, et al.
Publicado: (2009)

Rapid and efficient generation of neural progenitors from adult bone marrow stromal cells by hypoxic preconditioning
por: Mung, Kwan-Long, et al.
Publicado: (2016)

Hypoxic preconditioning enhances mesenchymal stromal cell lung repair capacity
por: Cruz, Fernanda Ferreira, et al.
Publicado: (2015)

Hypoxic Regulation of VEGF, HIF-1(alpha) in Coronary Collaterals Development
por: Sung, Ki Chul, et al.
Publicado: (2005)

HIF-1α increases the osteogenic capacity of ADSCs by coupling angiogenesis and osteogenesis via the HIF-1α/VEGF/AKT/mTOR signaling pathway
por: Song, Shuang, et al.
Publicado: (2023)

HIF-1α/Beclin1-Mediated Autophagy Is Involved in Neuroprotection Induced by Hypoxic Preconditioning
por: Lu, Na, et al.
Publicado: (2018)

Vandetanib (ZD6474) induces antiangiogenesis through mTOR–HIF-1 alpha–VEGF signaling axis in breast cancer cells
por: Li, Ling, et al.
Publicado: (2018)

VEGF-mTOR signaling links obesity and endometrial cancer
por: Sahoo, Subhransu S., et al.
Publicado: (2018)

Hypoxic preconditioning protection is eliminated in HIF-1α knockout mice subjected to neonatal hypoxia-ischemia
por: Sheldon, R. Ann, et al.
Publicado: (2014)

Epigenetic mechanisms of hypoxic preconditioning
por: Rybnikova, Elena, et al.
Publicado: (2015)

Cerebral Ischemic Preconditioning Aggravates Death of Oligodendrocytes
por: Guan, Teng, et al.
Publicado: (2022)

STAT3 and mTOR: co-operating to drive HIF and angiogenesis
por: Dodd, Kayleigh M., et al.
Publicado: (2015)

HIF is not essential for suppression of experimental tumor growth by mTOR inhibition
por: Knaup, Karl X., et al.
Publicado: (2017)

mTOR: a link from the extracellular milieu to transcriptional regulation of oligodendrocyte development
por: Wood, Teresa L., et al.
Publicado: (2013)

FIR-preconditioning promotes Akt-mTOR-exosome manufacture in cooperation with MITF to boost resilience of rat bone marrow-derived stem cells
por: Jeong, Yun-Mi, et al.
Publicado: (2023)

Adiponectin promotes VEGF-A-dependent angiogenesis in human chondrosarcoma through PI3K, Akt, mTOR, and HIF-α pathway
por: Lee, Hsiang-Ping, et al.
Publicado: (2015)

miRNA-29 aggravates myocardial infarction via inhibiting the PI3K/mTOR/HIF1α/VEGF pathway
por: Wang, Xiaoxi, et al.
Publicado: (2022)

Positive effects of hypoxic preconditioning of the extracellular matrix and stromal vascular fraction from adipose tissue
por: Dirat, Béatrice, et al.
Publicado: (2023)

Lymphangiogenesis in Gastric Cancer regulated through Akt/mTOR-VEGF-C/VEGF-D axis
por: Chen, Hongxia, et al.
Publicado: (2015)

The antihypertension drug doxazosin inhibits tumor growth and angiogenesis by decreasing VEGFR-2/Akt/mTOR signaling and VEGF and HIF-1α expression
por: Park, Mi Sun, et al.
Publicado: (2014)

Fasting promotes acute hypoxic adaptation by suppressing mTOR-mediated pathways
por: Zhao, Ruzhou, et al.
Publicado: (2021)

Hypoxic Preconditioning Promotes the Bioactivities of Mesenchymal Stem Cells via the HIF-1α-GRP78-Akt Axis
por: Lee, Jun Hee, et al.
Publicado: (2017)

Protective Effect of Hypoxic Preconditioning on Hypoxic-Ischemic Injured Newborn Rats
por: Park, Hyun-Kyung, et al.
Publicado: (2011)

The Effect of Hypoxic Preconditioning on Induced Schwann Cells under Hypoxic Conditions
por: Chen, Ou, et al.
Publicado: (2015)

Epigenetic downregulation of STAT6 increases HIF-1α expression via mTOR/S6K/S6, leading to enhanced hypoxic viability of glioma cells
por: Park, Soo Jung, et al.
Publicado: (2019)

Derivation of Oligodendrocyte Precursors from Adult Bone Marrow Stromal Cells for Remyelination Therapy
por: Tsui, Yat-Ping, et al.
Publicado: (2021)

The Galvanotactic Migration of Keratinocytes is Enhanced by Hypoxic Preconditioning
por: Guo, Xiaowei, et al.
Publicado: (2015)

Melittin Suppresses HIF-1α/VEGF Expression through Inhibition of ERK and mTOR/p70S6K Pathway in Human Cervical Carcinoma Cells
por: Shin, Jae-Moon, et al.
Publicado: (2013)

Berberine improves insulin-induced diabetic retinopathy through exclusively suppressing Akt/mTOR-mediated HIF-1α/VEGF activation in retina endothelial cells
por: Wang, Ning, et al.
Publicado: (2021)

Hypoxic Preconditioning Increases Survival and Pro-Angiogenic Capacity of Human Cord Blood Mesenchymal Stromal Cells In Vitro
por: Bader, Andreas Matthäus, et al.
Publicado: (2015)

Gene Expression Profile of Human Mesenchymal Stromal Cells Exposed to Hypoxic and Pseudohypoxic Preconditioning—An Analysis by RNA Sequencing
por: Zielniok, Katarzyna, et al.
Publicado: (2021)

Hypoxic-Preconditioned Bone Marrow Stem Cell Medium Significantly Improves Outcome After Retinal Ischemia in Rats
por: Roth, Steven, et al.
Publicado: (2016)

Autophagy mediates the beneficial effect of hypoxic preconditioning on bone marrow mesenchymal stem cells for the therapy of myocardial infarction
por: Zhang, Zheng, et al.
Publicado: (2017)

Hyperoxia sensitizes hypoxic HeLa cells to ionizing radiation by downregulating HIF-1α and VEGF expression
por: Dong, Dan, et al.
Publicado: (2021)

Leucine-Rich Glioma Inactivated 1 Promotes Oligodendrocyte Differentiation and Myelination via TSC-mTOR Signaling
por: Xie, Ya-Jun, et al.
Publicado: (2018)

mTOR/autophagy pathway in the hippocampus of rats suffering intermittent hypoxia preconditioning and global cerebral ischemia-reperfusion
por: Zhao, Ya-Ning, et al.
Publicado: (2017)

HIF-mediated Suppression of DEPTOR Confers Resistance to mTOR Kinase Inhibition in Renal Cancer
por: Doan, Hong, et al.
Publicado: (2019)

Inhibition of Protein Kinase C Delta Attenuates Allergic Airway Inflammation through Suppression of PI3K/Akt/mTOR/HIF-1 Alpha/VEGF Pathway
por: Choi, Yun Ho, et al.
Publicado: (2013)

Preconditioning of Rat Bone Marrow-Derived Mesenchymal Stromal Cells with Toll-Like Receptor Agonists
por: Evaristo-Mendonça, Fabiana, et al.
Publicado: (2019)

Plumbagin Suppresses Breast Cancer Progression by Downregulating HIF-1α Expression via a PI3K/Akt/mTOR Independent Pathway under Hypoxic Condition
por: Jampasri, Supawan, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_488efgkiph5ka751kidvj8c3gq