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Dealing With Liver Transplantation during Coronavirus Disease 2019 Pandemic: Normothermic Machine Perfusion Enables for Donor, Organ, and Recipient Assessment: A Case Report
The coronavirus disease 2019 (COVID-19) pandemic has changed life on a global scale. The numbers of transplantations have plummeted as a result of fear of disease transmission, recipient coronavirus disease 2019 infection, priority shift, and resource limitations. Severe acute respiratory syndrome c...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Author(s). Published by Elsevier Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7375284/ https://www.ncbi.nlm.nih.gov/pubmed/32800515 http://dx.doi.org/10.1016/j.transproceed.2020.07.011 |
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author | Bogensperger, Christina Cardini, Benno Oberhuber, Rupert Weissenbacher, Annemarie Gasteiger, Silvia Berchtold, Valeria Otarashvili, Giorgi Öfner, Dietmar Schneeberger, Stefan |
author_facet | Bogensperger, Christina Cardini, Benno Oberhuber, Rupert Weissenbacher, Annemarie Gasteiger, Silvia Berchtold, Valeria Otarashvili, Giorgi Öfner, Dietmar Schneeberger, Stefan |
author_sort | Bogensperger, Christina |
collection | PubMed |
description | The coronavirus disease 2019 (COVID-19) pandemic has changed life on a global scale. The numbers of transplantations have plummeted as a result of fear of disease transmission, recipient coronavirus disease 2019 infection, priority shift, and resource limitations. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) complicates transplantation because donor testing, (re)allocation of limited resources, and recipient testing may exceed permissible ischemia times. Normothermic machine perfusion (NMP) helps safely prolong liver preservation up to 38 hours. Additional time is essential under the current circumstances. Here we present the case of a 29-year-old liver transplant recipient in whom prolonged liver preservation required for SARS-CoV-2 screening was accomplished through NMP. Donor and recipient test results for SARS-CoV-2 were negative, and intensive care unit capacity was eventually available. The surgical procedure and postoperative course were uneventful. NMP can extend preservation times in liver transplantation while awaiting SARS-CoV-2 test results and available intensive care unit capacity. |
format | Online Article Text |
id | pubmed-7375284 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | The Author(s). Published by Elsevier Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-73752842020-07-23 Dealing With Liver Transplantation during Coronavirus Disease 2019 Pandemic: Normothermic Machine Perfusion Enables for Donor, Organ, and Recipient Assessment: A Case Report Bogensperger, Christina Cardini, Benno Oberhuber, Rupert Weissenbacher, Annemarie Gasteiger, Silvia Berchtold, Valeria Otarashvili, Giorgi Öfner, Dietmar Schneeberger, Stefan Transplant Proc COVID-19 Minisymposium: Towards a Strategic Roadmap The coronavirus disease 2019 (COVID-19) pandemic has changed life on a global scale. The numbers of transplantations have plummeted as a result of fear of disease transmission, recipient coronavirus disease 2019 infection, priority shift, and resource limitations. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) complicates transplantation because donor testing, (re)allocation of limited resources, and recipient testing may exceed permissible ischemia times. Normothermic machine perfusion (NMP) helps safely prolong liver preservation up to 38 hours. Additional time is essential under the current circumstances. Here we present the case of a 29-year-old liver transplant recipient in whom prolonged liver preservation required for SARS-CoV-2 screening was accomplished through NMP. Donor and recipient test results for SARS-CoV-2 were negative, and intensive care unit capacity was eventually available. The surgical procedure and postoperative course were uneventful. NMP can extend preservation times in liver transplantation while awaiting SARS-CoV-2 test results and available intensive care unit capacity. The Author(s). Published by Elsevier Inc. 2020-11 2020-07-22 /pmc/articles/PMC7375284/ /pubmed/32800515 http://dx.doi.org/10.1016/j.transproceed.2020.07.011 Text en © 2020 The Author(s) Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active. |
spellingShingle | COVID-19 Minisymposium: Towards a Strategic Roadmap Bogensperger, Christina Cardini, Benno Oberhuber, Rupert Weissenbacher, Annemarie Gasteiger, Silvia Berchtold, Valeria Otarashvili, Giorgi Öfner, Dietmar Schneeberger, Stefan Dealing With Liver Transplantation during Coronavirus Disease 2019 Pandemic: Normothermic Machine Perfusion Enables for Donor, Organ, and Recipient Assessment: A Case Report |
title | Dealing With Liver Transplantation during Coronavirus Disease 2019 Pandemic: Normothermic Machine Perfusion Enables for Donor, Organ, and Recipient Assessment: A Case Report |
title_full | Dealing With Liver Transplantation during Coronavirus Disease 2019 Pandemic: Normothermic Machine Perfusion Enables for Donor, Organ, and Recipient Assessment: A Case Report |
title_fullStr | Dealing With Liver Transplantation during Coronavirus Disease 2019 Pandemic: Normothermic Machine Perfusion Enables for Donor, Organ, and Recipient Assessment: A Case Report |
title_full_unstemmed | Dealing With Liver Transplantation during Coronavirus Disease 2019 Pandemic: Normothermic Machine Perfusion Enables for Donor, Organ, and Recipient Assessment: A Case Report |
title_short | Dealing With Liver Transplantation during Coronavirus Disease 2019 Pandemic: Normothermic Machine Perfusion Enables for Donor, Organ, and Recipient Assessment: A Case Report |
title_sort | dealing with liver transplantation during coronavirus disease 2019 pandemic: normothermic machine perfusion enables for donor, organ, and recipient assessment: a case report |
topic | COVID-19 Minisymposium: Towards a Strategic Roadmap |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7375284/ https://www.ncbi.nlm.nih.gov/pubmed/32800515 http://dx.doi.org/10.1016/j.transproceed.2020.07.011 |
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