Identification of Novel Alleles and Structural Haplotypes of Major Histocompatibility Complex Class I and DRB Genes in Domestic Cat (Felis catus) by a Newly Developed NGS-Based Genotyping Method

The major histocompatibility complex (MHC) is a highly polymorphic and duplicated genomic region that encodes transplantation and immune regulatory molecules. Although it is well-known that particular MHC allelic polymorphisms and haplotypes are genetically relate to immune-mediated diseases detaile...

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Detalles Bibliográficos
Autores principales: Okano, Masaharu, Miyamae, Jiro, Suzuki, Shingo, Nishiya, Kohei, Katakura, Fumihiko, Kulski, Jerzy K., Moritomo, Tadaaki, Shiina, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7375346/
https://www.ncbi.nlm.nih.gov/pubmed/32760428
http://dx.doi.org/10.3389/fgene.2020.00750

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