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Prevention and treatment of HIV infection and cognitive disease in mice by innate immune responses

HIV associated neurocognitive impairment afflicts roughly half of infected individuals on antiretroviral therapy. This disease currently has no treatment. We have previously shown that type I interferon is induced by and partially controls infection and neuropathogenesis in mice infected by chimeric...

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Detalles Bibliográficos
Autores principales: Dong, Baojun, Borjabad, Alejandra, Kelschenbach, Jennifer, Chao, Wei, Volsky, David J., Potash, Mary Jane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7375446/
https://www.ncbi.nlm.nih.gov/pubmed/32699842
http://dx.doi.org/10.1016/j.bbih.2020.100054