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Post-traumatic osteoarthritis development is not modified by postnatal chondrocyte deletion of Ccn2

CCN2 is a matricellular protein involved in several crucial biological processes. In particular, CCN2 is involved in cartilage development and in osteoarthritis. Ccn2 null mice exhibit a range of skeletal dysmorphisms, highlighting its importance in regulating matrix formation during development; ho...

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Detalles Bibliográficos
Autores principales: Keenan, Craig M., Ramos-Mucci, Lorenzo, Kanakis, Ioannis, Milner, Peter I., Leask, Andrew, Abraham, David, Bou-Gharios, George, Poulet, Blandine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7375478/
https://www.ncbi.nlm.nih.gov/pubmed/32616521
http://dx.doi.org/10.1242/dmm.044719