Accelerated partial breast irradiation with interstitial multicatheter brachytherapy after breast-conserving surgery for low-risk early breast cancer

Patients with low-risk invasive ductal carcinoma treated with breast-conserving surgery (BCS) were included in a multicatheter brachytherapy APBI protocol. The primary endpoint was ipsilateral breast recurrence. Between December 2008–December 2017, 186 low-risk breast cancer patients were treated wi...

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Autores principales: Rodriguez-Ibarria, Nieves G., Pinar, Ma Beatriz, García, Laura, Cabezón, M. Auxiliadora, Lloret, Marta, Rey-Baltar, Ma Dolores, Rdguez-Melcón, J. Ignacio, Lara, Pedro C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7375648/
https://www.ncbi.nlm.nih.gov/pubmed/32380439
http://dx.doi.org/10.1016/j.breast.2020.04.008
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author Rodriguez-Ibarria, Nieves G.
Pinar, Ma Beatriz
García, Laura
Cabezón, M. Auxiliadora
Lloret, Marta
Rey-Baltar, Ma Dolores
Rdguez-Melcón, J. Ignacio
Lara, Pedro C.
author_facet Rodriguez-Ibarria, Nieves G.
Pinar, Ma Beatriz
García, Laura
Cabezón, M. Auxiliadora
Lloret, Marta
Rey-Baltar, Ma Dolores
Rdguez-Melcón, J. Ignacio
Lara, Pedro C.
author_sort Rodriguez-Ibarria, Nieves G.
collection PubMed
description Patients with low-risk invasive ductal carcinoma treated with breast-conserving surgery (BCS) were included in a multicatheter brachytherapy APBI protocol. The primary endpoint was ipsilateral breast recurrence. Between December 2008–December 2017, 186 low-risk breast cancer patients were treated with APBI using interstitial multicatheter brachytherapy and followed prospectively. At 5-years of follow-up, cumulative local recurrence (LR) and cause-specific survival was 1.1% (95% CI 0.3–1.9) and 98.3% (95% CI 97.3–99.3%) respectively. No grade 3 adverse effects were observed. Postoperative APBI using multicatheter brachytherapy after BCS in early breast cancer patients have excellent rates of local control and survival, without significant toxicity.
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spelling pubmed-73756482020-07-29 Accelerated partial breast irradiation with interstitial multicatheter brachytherapy after breast-conserving surgery for low-risk early breast cancer Rodriguez-Ibarria, Nieves G. Pinar, Ma Beatriz García, Laura Cabezón, M. Auxiliadora Lloret, Marta Rey-Baltar, Ma Dolores Rdguez-Melcón, J. Ignacio Lara, Pedro C. Breast Short Communication Patients with low-risk invasive ductal carcinoma treated with breast-conserving surgery (BCS) were included in a multicatheter brachytherapy APBI protocol. The primary endpoint was ipsilateral breast recurrence. Between December 2008–December 2017, 186 low-risk breast cancer patients were treated with APBI using interstitial multicatheter brachytherapy and followed prospectively. At 5-years of follow-up, cumulative local recurrence (LR) and cause-specific survival was 1.1% (95% CI 0.3–1.9) and 98.3% (95% CI 97.3–99.3%) respectively. No grade 3 adverse effects were observed. Postoperative APBI using multicatheter brachytherapy after BCS in early breast cancer patients have excellent rates of local control and survival, without significant toxicity. Elsevier 2020-04-22 /pmc/articles/PMC7375648/ /pubmed/32380439 http://dx.doi.org/10.1016/j.breast.2020.04.008 Text en © 2020 The Author(s) http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Short Communication
Rodriguez-Ibarria, Nieves G.
Pinar, Ma Beatriz
García, Laura
Cabezón, M. Auxiliadora
Lloret, Marta
Rey-Baltar, Ma Dolores
Rdguez-Melcón, J. Ignacio
Lara, Pedro C.
Accelerated partial breast irradiation with interstitial multicatheter brachytherapy after breast-conserving surgery for low-risk early breast cancer
title Accelerated partial breast irradiation with interstitial multicatheter brachytherapy after breast-conserving surgery for low-risk early breast cancer
title_full Accelerated partial breast irradiation with interstitial multicatheter brachytherapy after breast-conserving surgery for low-risk early breast cancer
title_fullStr Accelerated partial breast irradiation with interstitial multicatheter brachytherapy after breast-conserving surgery for low-risk early breast cancer
title_full_unstemmed Accelerated partial breast irradiation with interstitial multicatheter brachytherapy after breast-conserving surgery for low-risk early breast cancer
title_short Accelerated partial breast irradiation with interstitial multicatheter brachytherapy after breast-conserving surgery for low-risk early breast cancer
title_sort accelerated partial breast irradiation with interstitial multicatheter brachytherapy after breast-conserving surgery for low-risk early breast cancer
topic Short Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7375648/
https://www.ncbi.nlm.nih.gov/pubmed/32380439
http://dx.doi.org/10.1016/j.breast.2020.04.008
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