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Sequential immunohistochemistry and virtual image reconstruction using a single slide for quantitative KI67 measurement in breast cancer

OBJECTIVE: Ki67 is a prognostic and predictive marker in breast cancer (BC). However, manual scoring (MS) by visual assessment suffers from high inter-observer variability which limits its clinical use. Here, we developed a new digital image analysis (DIA) workflow, named KiQuant for automated scori...

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Detalles Bibliográficos
Autores principales:	Serna, Garazi, Simonetti, Sara, Fasani, Roberta, Pagliuca, Francesca, Guardia, Xavier, Gallego, Paqui, Jimenez, Jose, Peg, Vicente, Saura, Cristina, Eppenberger-Castori, Serenella, Ramon y Cajal, Santiago, Terracciano, Luigi, Nuciforo, Paolo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2020
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7375667/ https://www.ncbi.nlm.nih.gov/pubmed/32707454 http://dx.doi.org/10.1016/j.breast.2020.07.002

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