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Drug-Induced Liver Injury Module for Medical Students

INTRODUCTION: No published curricula exist to introduce medical students to drug-induced liver injury (DILI). However, DILI is the most common cause of acute liver failure in the US, and drug-drug interactions are tested on the USMLE Step 1. METHODS: We developed an independent study module to intro...

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Detalles Bibliográficos
Autores principales: Dilly, Christen K., Craven, Hannah J., Molleston, Jean P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Association of American Medical Colleges 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7375700/
https://www.ncbi.nlm.nih.gov/pubmed/32715088
http://dx.doi.org/10.15766/mep_2374-8265.10918
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author Dilly, Christen K.
Craven, Hannah J.
Molleston, Jean P.
author_facet Dilly, Christen K.
Craven, Hannah J.
Molleston, Jean P.
author_sort Dilly, Christen K.
collection PubMed
description INTRODUCTION: No published curricula exist to introduce medical students to drug-induced liver injury (DILI). However, DILI is the most common cause of acute liver failure in the US, and drug-drug interactions are tested on the USMLE Step 1. METHODS: We developed an independent study module to introduce students to DILI. This module consisted of a narrated PowerPoint introduction, a journal article, and four example cases. Students completed the module independently. To evaluate the effectiveness of the activity, exam data and responses to the cases were reviewed, and end-of-course survey data were used. These responses were used to modify questions for clarity and to develop a feedback rubric. RESULTS: Mean scores on case-related questions in the module ranged from 44% to 73%. However, mean scores on test questions related to DILI ranged from 61% to 98%. It is possible that students learned from receiving feedback in the form of correct answers to the cases. On course evaluations, 52.4% of students agreed or strongly agreed that the online modules as a group (which included the DILI module) were an effective teaching method. DISCUSSION: This module introduces students to DILI and enables them to interact with valuable resources. We hope that modifications will improve the learning experience and effectiveness of the module. Going forward, we plan to collect validity evidence for the feedback rubric and develop an advanced version of the module for gastroenterology fellows.
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spelling pubmed-73757002020-07-24 Drug-Induced Liver Injury Module for Medical Students Dilly, Christen K. Craven, Hannah J. Molleston, Jean P. MedEdPORTAL Original Publication INTRODUCTION: No published curricula exist to introduce medical students to drug-induced liver injury (DILI). However, DILI is the most common cause of acute liver failure in the US, and drug-drug interactions are tested on the USMLE Step 1. METHODS: We developed an independent study module to introduce students to DILI. This module consisted of a narrated PowerPoint introduction, a journal article, and four example cases. Students completed the module independently. To evaluate the effectiveness of the activity, exam data and responses to the cases were reviewed, and end-of-course survey data were used. These responses were used to modify questions for clarity and to develop a feedback rubric. RESULTS: Mean scores on case-related questions in the module ranged from 44% to 73%. However, mean scores on test questions related to DILI ranged from 61% to 98%. It is possible that students learned from receiving feedback in the form of correct answers to the cases. On course evaluations, 52.4% of students agreed or strongly agreed that the online modules as a group (which included the DILI module) were an effective teaching method. DISCUSSION: This module introduces students to DILI and enables them to interact with valuable resources. We hope that modifications will improve the learning experience and effectiveness of the module. Going forward, we plan to collect validity evidence for the feedback rubric and develop an advanced version of the module for gastroenterology fellows. Association of American Medical Colleges 2020-07-15 /pmc/articles/PMC7375700/ /pubmed/32715088 http://dx.doi.org/10.15766/mep_2374-8265.10918 Text en © 2020 Dilly et al. https://creativecommons.org/licenses/by-nc/4.0/This is an open-access publication distributed under the terms of the Creative Commons Attribution-NonCommercial (https://creativecommons.org/licenses/by-nc/4.0/) license.
spellingShingle Original Publication
Dilly, Christen K.
Craven, Hannah J.
Molleston, Jean P.
Drug-Induced Liver Injury Module for Medical Students
title Drug-Induced Liver Injury Module for Medical Students
title_full Drug-Induced Liver Injury Module for Medical Students
title_fullStr Drug-Induced Liver Injury Module for Medical Students
title_full_unstemmed Drug-Induced Liver Injury Module for Medical Students
title_short Drug-Induced Liver Injury Module for Medical Students
title_sort drug-induced liver injury module for medical students
topic Original Publication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7375700/
https://www.ncbi.nlm.nih.gov/pubmed/32715088
http://dx.doi.org/10.15766/mep_2374-8265.10918
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