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Nephronectin promotes breast cancer brain metastatic colonization via its integrin-binding domains

This study demonstrates a role for the extracellular matrix protein nephronectin (NPNT) in promoting experimental breast cancer brain metastasis, possibly through enhanced binding to- and migration through brain endothelial cells. With the introduction of more targeted breast cancer treatments, a pr...

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Detalles Bibliográficos
Autores principales: Magnussen, Synnøve Norvoll, Toraskar, Jimita, Wilhelm, Imola, Hasko, Janos, Figenschau, Stine Linn, Molnar, Judit, Seppola, Marit, Steigen, Sonja E., Steigedal, Tonje S., Hadler-Olsen, Elin, Krizbai, Istvan A., Svineng, Gunbjørg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7376038/
https://www.ncbi.nlm.nih.gov/pubmed/32699247
http://dx.doi.org/10.1038/s41598-020-69242-1