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Nephronectin promotes breast cancer brain metastatic colonization via its integrin-binding domains
This study demonstrates a role for the extracellular matrix protein nephronectin (NPNT) in promoting experimental breast cancer brain metastasis, possibly through enhanced binding to- and migration through brain endothelial cells. With the introduction of more targeted breast cancer treatments, a pr...
Autores principales: | Magnussen, Synnøve Norvoll, Toraskar, Jimita, Wilhelm, Imola, Hasko, Janos, Figenschau, Stine Linn, Molnar, Judit, Seppola, Marit, Steigen, Sonja E., Steigedal, Tonje S., Hadler-Olsen, Elin, Krizbai, Istvan A., Svineng, Gunbjørg |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7376038/ https://www.ncbi.nlm.nih.gov/pubmed/32699247 http://dx.doi.org/10.1038/s41598-020-69242-1 |
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