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Mutational spectrum and prognosis in NRAS-mutated acute myeloid leukemia
The mutational spectrum and prognostic factors of NRAS-mutated (NRAS(mut)) acute myeloid leukemia (AML) are largely unknown. We performed next-generation sequencing (NGS) in 1,149 cases of de novo AML and discovered 152 NRAS(mut) AML (13%). Of the 152 NRAS(mut) AML, 89% had at least one companion mu...
| Autores principales: | , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7376066/ https://www.ncbi.nlm.nih.gov/pubmed/32699322 http://dx.doi.org/10.1038/s41598-020-69194-6 |