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Glycolaldehyde-modified proteins cause adverse functional and structural aortic remodeling leading to cardiac pressure overload

Growing evidence supports the role of advanced glycation end products (AGEs) in the development of diabetic vascular complications and cardiovascular diseases (CVDs). We have shown that high-molecular-weight AGEs (HMW-AGEs), present in our Western diet, impair cardiac function. Whether HMW-AGEs affe...

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Detalles Bibliográficos
Autores principales: Haesen, Sibren, Cöl, Ümare, Schurgers, Wouter, Evens, Lize, Verboven, Maxim, Driesen, Ronald B., Bronckaers, Annelies, Lambrichts, Ivo, Deluyker, Dorien, Bito, Virginie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7376068/
https://www.ncbi.nlm.nih.gov/pubmed/32699285
http://dx.doi.org/10.1038/s41598-020-68974-4

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