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Glycolaldehyde-modified proteins cause adverse functional and structural aortic remodeling leading to cardiac pressure overload
Growing evidence supports the role of advanced glycation end products (AGEs) in the development of diabetic vascular complications and cardiovascular diseases (CVDs). We have shown that high-molecular-weight AGEs (HMW-AGEs), present in our Western diet, impair cardiac function. Whether HMW-AGEs affe...
Autores principales: | Haesen, Sibren, Cöl, Ümare, Schurgers, Wouter, Evens, Lize, Verboven, Maxim, Driesen, Ronald B., Bronckaers, Annelies, Lambrichts, Ivo, Deluyker, Dorien, Bito, Virginie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7376068/ https://www.ncbi.nlm.nih.gov/pubmed/32699285 http://dx.doi.org/10.1038/s41598-020-68974-4 |
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