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The hot sites of α-synuclein in amyloid fibril formation

The role of alpha-synuclein (αS) amyloid fibrillation has been recognized in various neurological diseases including Parkinson’s Disease (PD). In early stages, fibrillation occurs by the structural transition from helix to extended states in monomeric αS followed by the formation of beta-sheets. Thi...

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Detalles Bibliográficos
Autores principales:	Khammari, Anahita, Arab, Seyed Shahriar, Ejtehadi, Mohammad Reza
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7376172/ https://www.ncbi.nlm.nih.gov/pubmed/32699326 http://dx.doi.org/10.1038/s41598-020-68887-2

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