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Stress and behavioral correlates in the head-fixed method: stress measurements, habituation dynamics, locomotion, and motor-skill learning in mice
Manual restriction of head movement, or head-fixation, of awake rodents allows for sophisticated investigation of neural circuits in vivo, that would otherwise be impossible in completely freely moving animals. While it is known that head-fixation induces stress, the scale of this stress and habitua...
Autores principales: | Juczewski, Konrad, Koussa, Jonathan A., Kesner, Andrew J., Lee, Jeong O., Lovinger, David M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7376196/ https://www.ncbi.nlm.nih.gov/pubmed/32699235 http://dx.doi.org/10.1038/s41598-020-69132-6 |
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