Whole-blood expression of inflammasome- and glucocorticoid-related mRNAs correctly separates treatment-resistant depressed patients from drug-free and responsive patients in the BIODEP study

The mRNA expression signatures associated with the ‘pro-inflammatory’ phenotype of depression, and the differential signatures associated with depression subtypes and the effects of antidepressants, are still unknown. We examined 130 depressed patients (58 treatment-resistant, 36 antidepressant-resp...

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Detalles Bibliográficos
Autores principales: Cattaneo, Annamaria, Ferrari, Clarissa, Turner, Lorinda, Mariani, Nicole, Enache, Daniela, Hastings, Caitlin, Kose, Melisa, Lombardo, Giulia, McLaughlin, Anna P., Nettis, Maria A., Nikkheslat, Naghmeh, Sforzini, Luca, Worrell, Courtney, Zajkowska, Zuzanna, Cattane, Nadia, Lopizzo, Nicola, Mazzelli, Monica, Pointon, Linda, Cowen, Philip J., Cavanagh, Jonathan, Harrison, Neil A., de Boer, Peter, Jones, Declan, Drevets, Wayne C., Mondelli, Valeria, Bullmore, Edward T., Pariante, Carmine M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7376244/
https://www.ncbi.nlm.nih.gov/pubmed/32699209
http://dx.doi.org/10.1038/s41398-020-00874-7

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