MCD diet-induced steatohepatitis generates a diurnal rhythm of associated biomarkers and worsens liver injury in Klf10 deficient mice

A large number of hepatic functions are regulated by the circadian clock and recent evidence suggests that clock disruption could be a risk factor for liver complications. The circadian transcription factor Krüppel like factor 10 (KLF10) has been involved in liver metabolism as well as cellular infl...

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Detalles Bibliográficos
Autores principales: Leclère, Pierre S., Rousseau, Déborah, Patouraux, Stéphanie, Guérin, Sophie, Bonnafous, Stéphanie, Gréchez-Cassiau, Aline, Ruberto, Anthony A., Luci, Carmelo, Subramaniam, Malayannan, Tran, Albert, Delaunay, Franck, Gual, Philippe, Teboul, Michèle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7376252/
https://www.ncbi.nlm.nih.gov/pubmed/32699233
http://dx.doi.org/10.1038/s41598-020-69085-w

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