Confounding factors of non-invasive tests for nonalcoholic fatty liver disease

Nonalcoholic fatty liver disease (NAFLD) affects at least 25% of the general adult population worldwide. Because only a fraction of the patients would develop liver-related complications, it is preferable to perform non-invasive tests as the initial assessment. This review summarizes the known and p...

Descripción completa

Detalles Bibliográficos
Autores principales: Wai, Janae Wentong, Fu, Charmaine, Wong, Vincent Wai-Sun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7376510/
https://www.ncbi.nlm.nih.gov/pubmed/32451628
http://dx.doi.org/10.1007/s00535-020-01686-8
_version_ 1783562057370566656
author Wai, Janae Wentong
Fu, Charmaine
Wong, Vincent Wai-Sun
author_facet Wai, Janae Wentong
Fu, Charmaine
Wong, Vincent Wai-Sun
author_sort Wai, Janae Wentong
collection PubMed
description Nonalcoholic fatty liver disease (NAFLD) affects at least 25% of the general adult population worldwide. Because only a fraction of the patients would develop liver-related complications, it is preferable to perform non-invasive tests as the initial assessment. This review summarizes the known and potential confounding factors that affect the performance of non-invasive tests of hepatic steatosis and fibrosis in patients with NAFLD. Clinicians may apply the knowledge and exercise caution in selecting investigations and interpreting test results when confounding factors are present.
format Online
Article
Text
id pubmed-7376510
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher Springer Singapore
record_format MEDLINE/PubMed
spelling pubmed-73765102020-07-27 Confounding factors of non-invasive tests for nonalcoholic fatty liver disease Wai, Janae Wentong Fu, Charmaine Wong, Vincent Wai-Sun J Gastroenterol Review Nonalcoholic fatty liver disease (NAFLD) affects at least 25% of the general adult population worldwide. Because only a fraction of the patients would develop liver-related complications, it is preferable to perform non-invasive tests as the initial assessment. This review summarizes the known and potential confounding factors that affect the performance of non-invasive tests of hepatic steatosis and fibrosis in patients with NAFLD. Clinicians may apply the knowledge and exercise caution in selecting investigations and interpreting test results when confounding factors are present. Springer Singapore 2020-05-25 2020 /pmc/articles/PMC7376510/ /pubmed/32451628 http://dx.doi.org/10.1007/s00535-020-01686-8 Text en © The Author(s) 2020 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Review
Wai, Janae Wentong
Fu, Charmaine
Wong, Vincent Wai-Sun
Confounding factors of non-invasive tests for nonalcoholic fatty liver disease
title Confounding factors of non-invasive tests for nonalcoholic fatty liver disease
title_full Confounding factors of non-invasive tests for nonalcoholic fatty liver disease
title_fullStr Confounding factors of non-invasive tests for nonalcoholic fatty liver disease
title_full_unstemmed Confounding factors of non-invasive tests for nonalcoholic fatty liver disease
title_short Confounding factors of non-invasive tests for nonalcoholic fatty liver disease
title_sort confounding factors of non-invasive tests for nonalcoholic fatty liver disease
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7376510/
https://www.ncbi.nlm.nih.gov/pubmed/32451628
http://dx.doi.org/10.1007/s00535-020-01686-8
work_keys_str_mv AT waijanaewentong confoundingfactorsofnoninvasivetestsfornonalcoholicfattyliverdisease
AT fucharmaine confoundingfactorsofnoninvasivetestsfornonalcoholicfattyliverdisease
AT wongvincentwaisun confoundingfactorsofnoninvasivetestsfornonalcoholicfattyliverdisease

Ejemplares similares