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Astaxanthin alleviates spinal cord ischemia-reperfusion injury via activation of PI3K/Akt/GSK-3β pathway in rats
BACKGROUND: Ischemia-reperfusion injury of the spinal cord (SCII) often leads to unalterable neurological deficits, which may be associated with apoptosis induced by oxidative stress and inflammation. Astaxanthin (AST) is a strong antioxidant and anti-inflammatory agent with multitarget neuroprotect...
Autores principales: | Fu, Jian, Sun, Haibin, Wei, Haofei, Dong, Mingjie, Zhang, Yongzhe, Xu, Wei, Fang, Yanwei, Zhao, Jianhui |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7376638/ https://www.ncbi.nlm.nih.gov/pubmed/32703256 http://dx.doi.org/10.1186/s13018-020-01790-8 |
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