A narrative review of estimands in drug development and regulatory evaluation: old wine in new barrels?

BACKGROUND: An estimand defines the target of estimation for a clinical trial through specification of the treatment, target population, variable, population-level summary and of the strategies for intercurrent events. A carefully defined estimand aligns the clinical trial design and analysis with t...

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Detalles Bibliográficos
Autores principales: Mitroiu, M., Oude Rengerink, K., Teerenstra, S., Pétavy, F., Roes, K. C. B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7376663/
https://www.ncbi.nlm.nih.gov/pubmed/32703247
http://dx.doi.org/10.1186/s13063-020-04546-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7376663/
https://www.ncbi.nlm.nih.gov/pubmed/32703247
http://dx.doi.org/10.1186/s13063-020-04546-1

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