NLRP3 inflammasome-mediated microglial pyroptosis is critically involved in the development of post-cardiac arrest brain injury

BACKGROUND: Brain injury is the leading cause of death and disability in survivors of cardiac arrest, where neuroinflammation is believed to play a pivotal role, but the underlying mechanism remains unclear. Pyroptosis is a pro-inflammatory form of programmed cell death that triggers inflammatory re...

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Detalles Bibliográficos
Autores principales: Chang, Yuan, Zhu, Juan, Wang, Di, Li, Hua, He, Yihua, Liu, Kewei, Wang, Xiaoqiang, Peng, Yuqin, Pan, Suyue, Huang, Kaibin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7376727/
https://www.ncbi.nlm.nih.gov/pubmed/32703306
http://dx.doi.org/10.1186/s12974-020-01879-1

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