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Rationale for Timely Insulin Therapy in Type 2 Diabetes Within the Framework of Individualised Treatment: 2020 Update

Type 2 diabetes is characterised by chronic hyperglycaemia and variable degrees of insulin deficiency and resistance. Hyperglycaemia and elevated fatty acids exert harmful effects on β-cell function, regeneration and apoptosis (gluco-lipotoxicity). Furthermore, chronic hyperglycaemia triggers a vici...

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Detalles Bibliográficos
Autores principales: Hanefeld, Markolf, Fleischmann, Holger, Siegmund, Thorsten, Seufert, Jochen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Healthcare 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7376805/
https://www.ncbi.nlm.nih.gov/pubmed/32564335
http://dx.doi.org/10.1007/s13300-020-00855-5