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Protocol of the QUATTRO-II study: a multicenter randomized phase II study comparing CAPOXIRI plus bevacizumab with FOLFOXIRI plus bevacizumab as a first-line treatment in patients with metastatic colorectal cancer
BACKGROUND: First-line treatment with FOLFOXIRI plus bevacizumab (BEV) is highly effective and regarded as one of the standards-of-care for patients with metastatic colorectal cancer (mCRC), despite the high incidence of neutropenia and diarrhea as side effects. AXEPT, an Asian phase III study, show...
Autores principales: | Miyo, Masaaki, Kato, Takeshi, Yoshino, Takayuki, Yamanaka, Takeharu, Bando, Hideaki, Satake, Hironaga, Yamazaki, Kentaro, Taniguchi, Hiroya, Oki, Eiji, Kotaka, Masahito, Oba, Koji, Miyata, Yoshinori, Muro, Kei, Komatsu, Yoshito, Baba, Hideo, Tsuji, Akihito |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7376863/ https://www.ncbi.nlm.nih.gov/pubmed/32703200 http://dx.doi.org/10.1186/s12885-020-07186-5 |
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