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dUMP/F-dUMP Binding to Thymidylate Synthase: Human Versus Mycobacterium tuberculosis
[Image: see text] Thymidylate synthase is an enzyme that catalyzes deoxythymidine monophosphate (dTMP) synthesis from substrate deoxyuridine monophosphate (dUMP). Thymidylate synthase of Mycobacterium tuberculosis (MtbThyX) is structurally distinct from its human analogue human thymidylate synthase...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7376888/ https://www.ncbi.nlm.nih.gov/pubmed/32715203 http://dx.doi.org/10.1021/acsomega.0c01224 |