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dUMP/F-dUMP Binding to Thymidylate Synthase: Human Versus Mycobacterium tuberculosis

[Image: see text] Thymidylate synthase is an enzyme that catalyzes deoxythymidine monophosphate (dTMP) synthesis from substrate deoxyuridine monophosphate (dUMP). Thymidylate synthase of Mycobacterium tuberculosis (MtbThyX) is structurally distinct from its human analogue human thymidylate synthase...

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Detalles Bibliográficos
Autores principales: Gaurav, Kumar, Adhikary, Tiasha, Satpati, Priyadarshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7376888/
https://www.ncbi.nlm.nih.gov/pubmed/32715203
http://dx.doi.org/10.1021/acsomega.0c01224