Neutrophil Counts in Healthy South African Infants: Implications for Enrollment and Adverse Event Grading in Clinical Trials in an African Setting

Absolute neutrophil counts are used to assess eligibility and safety during clinical trials but the toxicity grading scale used can affect enrollment and reporting of adverse events. During a trial investigating a parenteral rotavirus vaccine in South Africa, we excluded otherwise healthy infants wi...

Descripción completa

Detalles Bibliográficos
Autores principales: Koen, Anthonet, Jose, Lisa, Madhi, Shabir A., Fix, Alan, Cryz, Stanley, Groome, Michelle J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Brief Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7376988/
https://www.ncbi.nlm.nih.gov/pubmed/32734176
http://dx.doi.org/10.1016/j.ympdx.2019.100005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7376988/
https://www.ncbi.nlm.nih.gov/pubmed/32734176
http://dx.doi.org/10.1016/j.ympdx.2019.100005

Ejemplares similares