Cargando…
Potential Drugs and Remedies for the Treatment of COVID-19: a Critical Review
ABSTRACT: COVID-19 disease with a high rate of contagious and highly nonspecific symptoms, is an infectious disease caused by a newly discovered coronavirus. Most people who fall sick with COVID-19 will experience mild to moderate symptoms such as respiratory symptoms, cough, dyspnea, fever, and vir...
Autores principales: | , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7377207/ https://www.ncbi.nlm.nih.gov/pubmed/32754003 http://dx.doi.org/10.1186/s12575-020-00129-1 |
_version_ | 1783562180003627008 |
---|---|
author | Barati, Fatemeh Pouresmaieli, Mahdi Ekrami, Elena Asghari, Sahar Ziarani, Farzad Ramezani Mamoudifard, Matin |
author_facet | Barati, Fatemeh Pouresmaieli, Mahdi Ekrami, Elena Asghari, Sahar Ziarani, Farzad Ramezani Mamoudifard, Matin |
author_sort | Barati, Fatemeh |
collection | PubMed |
description | ABSTRACT: COVID-19 disease with a high rate of contagious and highly nonspecific symptoms, is an infectious disease caused by a newly discovered coronavirus. Most people who fall sick with COVID-19 will experience mild to moderate symptoms such as respiratory symptoms, cough, dyspnea, fever, and viral pneumonia and recover without any special cure. However, some others need special and emergency treatment to get rid of this widespread disease. Till now, there are numbers of proposed novel compounds as well as standards therapeutics agent existed for other conditions seems to have efficacy against the 2019-nCoV. Some which are being tested for MERS-CoV and SARS-CoV are validated that could be also efficient against this new coronavirus. However, there are currently no effective specific antivirals or drug combinations introduced for 2019-nCoV specifically that be supported by high-level evidence. The main purpose of this paper is to review typical and ongoing treatments for coronavirus disease including home remedies, herbal medicine, chemical drugs, plasma therapy, and also vaccinies. In this regards, famous herbal medicines and common chemical drugs which are routinely to be prescribed for patients are introduced. Moreover, a section is assigned to the drug interactions and some outdated drugs which have been proved to be inefficient. We hope that this work could pave the way for researchers to develop faster and more reliable methods for earlier treatment of patients and rescue more people. GRAPHICAL ABSTRACT: [Image: see text] |
format | Online Article Text |
id | pubmed-7377207 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-73772072020-07-23 Potential Drugs and Remedies for the Treatment of COVID-19: a Critical Review Barati, Fatemeh Pouresmaieli, Mahdi Ekrami, Elena Asghari, Sahar Ziarani, Farzad Ramezani Mamoudifard, Matin Biol Proced Online Review ABSTRACT: COVID-19 disease with a high rate of contagious and highly nonspecific symptoms, is an infectious disease caused by a newly discovered coronavirus. Most people who fall sick with COVID-19 will experience mild to moderate symptoms such as respiratory symptoms, cough, dyspnea, fever, and viral pneumonia and recover without any special cure. However, some others need special and emergency treatment to get rid of this widespread disease. Till now, there are numbers of proposed novel compounds as well as standards therapeutics agent existed for other conditions seems to have efficacy against the 2019-nCoV. Some which are being tested for MERS-CoV and SARS-CoV are validated that could be also efficient against this new coronavirus. However, there are currently no effective specific antivirals or drug combinations introduced for 2019-nCoV specifically that be supported by high-level evidence. The main purpose of this paper is to review typical and ongoing treatments for coronavirus disease including home remedies, herbal medicine, chemical drugs, plasma therapy, and also vaccinies. In this regards, famous herbal medicines and common chemical drugs which are routinely to be prescribed for patients are introduced. Moreover, a section is assigned to the drug interactions and some outdated drugs which have been proved to be inefficient. We hope that this work could pave the way for researchers to develop faster and more reliable methods for earlier treatment of patients and rescue more people. GRAPHICAL ABSTRACT: [Image: see text] BioMed Central 2020-07-23 /pmc/articles/PMC7377207/ /pubmed/32754003 http://dx.doi.org/10.1186/s12575-020-00129-1 Text en © The Author(s) 2020, corrected publication 2023 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data. |
spellingShingle | Review Barati, Fatemeh Pouresmaieli, Mahdi Ekrami, Elena Asghari, Sahar Ziarani, Farzad Ramezani Mamoudifard, Matin Potential Drugs and Remedies for the Treatment of COVID-19: a Critical Review |
title | Potential Drugs and Remedies for the Treatment of COVID-19: a Critical Review |
title_full | Potential Drugs and Remedies for the Treatment of COVID-19: a Critical Review |
title_fullStr | Potential Drugs and Remedies for the Treatment of COVID-19: a Critical Review |
title_full_unstemmed | Potential Drugs and Remedies for the Treatment of COVID-19: a Critical Review |
title_short | Potential Drugs and Remedies for the Treatment of COVID-19: a Critical Review |
title_sort | potential drugs and remedies for the treatment of covid-19: a critical review |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7377207/ https://www.ncbi.nlm.nih.gov/pubmed/32754003 http://dx.doi.org/10.1186/s12575-020-00129-1 |
work_keys_str_mv | AT baratifatemeh potentialdrugsandremediesforthetreatmentofcovid19acriticalreview AT pouresmaielimahdi potentialdrugsandremediesforthetreatmentofcovid19acriticalreview AT ekramielena potentialdrugsandremediesforthetreatmentofcovid19acriticalreview AT asgharisahar potentialdrugsandremediesforthetreatmentofcovid19acriticalreview AT ziaranifarzadramezani potentialdrugsandremediesforthetreatmentofcovid19acriticalreview AT mamoudifardmatin potentialdrugsandremediesforthetreatmentofcovid19acriticalreview |