Aberrant RNA translation in fragile X syndrome: From FMRP mechanisms to emerging therapeutic strategies

Research in the past decades has unfolded the multifaceted role of Fragile X mental retardation protein (FMRP) and how its absence contributes to the pathophysiology of Fragile X syndrome (FXS). Excess signaling through group 1 metabotropic glutamate receptors is commonly observed in mouse models of...

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Detalles Bibliográficos
Autores principales: Banerjee, Anwesha, Ifrim, Marius F., Valdez, Arielle N., Raj, Nisha, Bassell, Gary J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7377270/
https://www.ncbi.nlm.nih.gov/pubmed/29653083
http://dx.doi.org/10.1016/j.brainres.2018.04.008

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7377270/
https://www.ncbi.nlm.nih.gov/pubmed/29653083
http://dx.doi.org/10.1016/j.brainres.2018.04.008

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