Genetic variability in the absorption of dietary sterols affects the risk of coronary artery disease

AIMS: To explore whether variability in dietary cholesterol and phytosterol absorption impacts the risk of coronary artery disease (CAD) using as instruments sequence variants in the ABCG5/8 genes, key regulators of intestinal absorption of dietary sterols. METHODS AND RESULTS: We examined the effec...

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Detalles Bibliográficos
Autores principales: Helgadottir, Anna, Thorleifsson, Gudmar, Alexandersson, Kristjan F, Tragante, Vinicius, Thorsteinsdottir, Margret, Eiriksson, Finnur F, Gretarsdottir, Solveig, Björnsson, Eythór, Magnusson, Olafur, Sveinbjornsson, Gardar, Jonsdottir, Ingileif, Steinthorsdottir, Valgerdur, Ferkingstad, Egil, Jensson, Brynjar Ö, Stefansson, Hreinn, Olafsson, Isleifur, Christensen, Alex H, Torp-Pedersen, Christian, Køber, Lars, Pedersen, Ole B, Erikstrup, Christian, Sørensen, Erik, Brunak, Søren, Banasik, Karina, Hansen, Thomas F, Nyegaard, Mette, Eyjolfssson, Gudmundur I, Sigurdardottir, Olof, Thorarinsson, Bjorn L, Matthiasson, Stefan E, Steingrimsdottir, Thora, Bjornsson, Einar S, Danielsen, Ragnar, Asselbergs, Folkert W, Arnar, David O, Ullum, Henrik, Bundgaard, Henning, Sulem, Patrick, Thorsteinsdottir, Unnur, Thorgeirsson, Gudmundur, Holm, Hilma, Gudbjartsson, Daniel F, Stefansson, Kari
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Basic Science
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7377579/
https://www.ncbi.nlm.nih.gov/pubmed/32702746
http://dx.doi.org/10.1093/eurheartj/ehaa531

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