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Unclear but present danger: An asymptomatic SARS-CoV-2 carrier

Superspreaders are critical infectious resources in multiple infectious diseases. They can be asymptomatic or present mild symptoms but can transmit pathogens to susceptible populations, leading to severe symptoms, and even death. Early identification of this population is extremely important to inh...

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Detalles Bibliográficos
Autores principales: Yu, Xuejing, Ran, Dongchuan, Wang, Jinhui, Qin, Yuan, Liu, Ruishan, Shi, Xueli, Wang, Yiping, Xie, Chang, Jiang, Jia, Zhou, Jianzhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chongqing Medical University 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7377777/
https://www.ncbi.nlm.nih.gov/pubmed/32837986
http://dx.doi.org/10.1016/j.gendis.2020.07.010
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author Yu, Xuejing
Ran, Dongchuan
Wang, Jinhui
Qin, Yuan
Liu, Ruishan
Shi, Xueli
Wang, Yiping
Xie, Chang
Jiang, Jia
Zhou, Jianzhong
author_facet Yu, Xuejing
Ran, Dongchuan
Wang, Jinhui
Qin, Yuan
Liu, Ruishan
Shi, Xueli
Wang, Yiping
Xie, Chang
Jiang, Jia
Zhou, Jianzhong
author_sort Yu, Xuejing
collection PubMed
description Superspreaders are critical infectious resources in multiple infectious diseases. They can be asymptomatic or present mild symptoms but can transmit pathogens to susceptible populations, leading to severe symptoms, and even death. Early identification of this population is extremely important to inhibit the spread of infectious diseases. Right now, the whole global world is suffering from a devastating infectious disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). In this article, a superspreader cluster event in coronavirus disease 2019 (COVID-19) was identified by tracking contacting histories of infected patients. This cluster was found to be originated from an asymptomatic SARS-CoV-2 carrier, which resulted in 13 secondary cases getting infected. All the secondary patients presented with non-typical symptoms of COVID-19, such as fever, dry cough, and myalgia, one of which died of respiratory failure at the end. From this cluster, we learn that people with older ages, low immunity, multiple underlying diseases, especially pulmonary diseases, can contribute to a poor prognosis. Thus, asymptomatic superspreaders of COVID-19 can be extremely dangerous and must be handled time-efficiently.
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spelling pubmed-73777772020-07-24 Unclear but present danger: An asymptomatic SARS-CoV-2 carrier Yu, Xuejing Ran, Dongchuan Wang, Jinhui Qin, Yuan Liu, Ruishan Shi, Xueli Wang, Yiping Xie, Chang Jiang, Jia Zhou, Jianzhong Genes Dis Full Length Article Superspreaders are critical infectious resources in multiple infectious diseases. They can be asymptomatic or present mild symptoms but can transmit pathogens to susceptible populations, leading to severe symptoms, and even death. Early identification of this population is extremely important to inhibit the spread of infectious diseases. Right now, the whole global world is suffering from a devastating infectious disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). In this article, a superspreader cluster event in coronavirus disease 2019 (COVID-19) was identified by tracking contacting histories of infected patients. This cluster was found to be originated from an asymptomatic SARS-CoV-2 carrier, which resulted in 13 secondary cases getting infected. All the secondary patients presented with non-typical symptoms of COVID-19, such as fever, dry cough, and myalgia, one of which died of respiratory failure at the end. From this cluster, we learn that people with older ages, low immunity, multiple underlying diseases, especially pulmonary diseases, can contribute to a poor prognosis. Thus, asymptomatic superspreaders of COVID-19 can be extremely dangerous and must be handled time-efficiently. Chongqing Medical University 2020-07-23 /pmc/articles/PMC7377777/ /pubmed/32837986 http://dx.doi.org/10.1016/j.gendis.2020.07.010 Text en © 2020 Chongqing Medical University. Production and hosting by Elsevier B.V. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Full Length Article
Yu, Xuejing
Ran, Dongchuan
Wang, Jinhui
Qin, Yuan
Liu, Ruishan
Shi, Xueli
Wang, Yiping
Xie, Chang
Jiang, Jia
Zhou, Jianzhong
Unclear but present danger: An asymptomatic SARS-CoV-2 carrier
title Unclear but present danger: An asymptomatic SARS-CoV-2 carrier
title_full Unclear but present danger: An asymptomatic SARS-CoV-2 carrier
title_fullStr Unclear but present danger: An asymptomatic SARS-CoV-2 carrier
title_full_unstemmed Unclear but present danger: An asymptomatic SARS-CoV-2 carrier
title_short Unclear but present danger: An asymptomatic SARS-CoV-2 carrier
title_sort unclear but present danger: an asymptomatic sars-cov-2 carrier
topic Full Length Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7377777/
https://www.ncbi.nlm.nih.gov/pubmed/32837986
http://dx.doi.org/10.1016/j.gendis.2020.07.010
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