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Unclear but present danger: An asymptomatic SARS-CoV-2 carrier
Superspreaders are critical infectious resources in multiple infectious diseases. They can be asymptomatic or present mild symptoms but can transmit pathogens to susceptible populations, leading to severe symptoms, and even death. Early identification of this population is extremely important to inh...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Chongqing Medical University
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7377777/ https://www.ncbi.nlm.nih.gov/pubmed/32837986 http://dx.doi.org/10.1016/j.gendis.2020.07.010 |
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author | Yu, Xuejing Ran, Dongchuan Wang, Jinhui Qin, Yuan Liu, Ruishan Shi, Xueli Wang, Yiping Xie, Chang Jiang, Jia Zhou, Jianzhong |
author_facet | Yu, Xuejing Ran, Dongchuan Wang, Jinhui Qin, Yuan Liu, Ruishan Shi, Xueli Wang, Yiping Xie, Chang Jiang, Jia Zhou, Jianzhong |
author_sort | Yu, Xuejing |
collection | PubMed |
description | Superspreaders are critical infectious resources in multiple infectious diseases. They can be asymptomatic or present mild symptoms but can transmit pathogens to susceptible populations, leading to severe symptoms, and even death. Early identification of this population is extremely important to inhibit the spread of infectious diseases. Right now, the whole global world is suffering from a devastating infectious disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). In this article, a superspreader cluster event in coronavirus disease 2019 (COVID-19) was identified by tracking contacting histories of infected patients. This cluster was found to be originated from an asymptomatic SARS-CoV-2 carrier, which resulted in 13 secondary cases getting infected. All the secondary patients presented with non-typical symptoms of COVID-19, such as fever, dry cough, and myalgia, one of which died of respiratory failure at the end. From this cluster, we learn that people with older ages, low immunity, multiple underlying diseases, especially pulmonary diseases, can contribute to a poor prognosis. Thus, asymptomatic superspreaders of COVID-19 can be extremely dangerous and must be handled time-efficiently. |
format | Online Article Text |
id | pubmed-7377777 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Chongqing Medical University |
record_format | MEDLINE/PubMed |
spelling | pubmed-73777772020-07-24 Unclear but present danger: An asymptomatic SARS-CoV-2 carrier Yu, Xuejing Ran, Dongchuan Wang, Jinhui Qin, Yuan Liu, Ruishan Shi, Xueli Wang, Yiping Xie, Chang Jiang, Jia Zhou, Jianzhong Genes Dis Full Length Article Superspreaders are critical infectious resources in multiple infectious diseases. They can be asymptomatic or present mild symptoms but can transmit pathogens to susceptible populations, leading to severe symptoms, and even death. Early identification of this population is extremely important to inhibit the spread of infectious diseases. Right now, the whole global world is suffering from a devastating infectious disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). In this article, a superspreader cluster event in coronavirus disease 2019 (COVID-19) was identified by tracking contacting histories of infected patients. This cluster was found to be originated from an asymptomatic SARS-CoV-2 carrier, which resulted in 13 secondary cases getting infected. All the secondary patients presented with non-typical symptoms of COVID-19, such as fever, dry cough, and myalgia, one of which died of respiratory failure at the end. From this cluster, we learn that people with older ages, low immunity, multiple underlying diseases, especially pulmonary diseases, can contribute to a poor prognosis. Thus, asymptomatic superspreaders of COVID-19 can be extremely dangerous and must be handled time-efficiently. Chongqing Medical University 2020-07-23 /pmc/articles/PMC7377777/ /pubmed/32837986 http://dx.doi.org/10.1016/j.gendis.2020.07.010 Text en © 2020 Chongqing Medical University. Production and hosting by Elsevier B.V. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Full Length Article Yu, Xuejing Ran, Dongchuan Wang, Jinhui Qin, Yuan Liu, Ruishan Shi, Xueli Wang, Yiping Xie, Chang Jiang, Jia Zhou, Jianzhong Unclear but present danger: An asymptomatic SARS-CoV-2 carrier |
title | Unclear but present danger: An asymptomatic SARS-CoV-2 carrier |
title_full | Unclear but present danger: An asymptomatic SARS-CoV-2 carrier |
title_fullStr | Unclear but present danger: An asymptomatic SARS-CoV-2 carrier |
title_full_unstemmed | Unclear but present danger: An asymptomatic SARS-CoV-2 carrier |
title_short | Unclear but present danger: An asymptomatic SARS-CoV-2 carrier |
title_sort | unclear but present danger: an asymptomatic sars-cov-2 carrier |
topic | Full Length Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7377777/ https://www.ncbi.nlm.nih.gov/pubmed/32837986 http://dx.doi.org/10.1016/j.gendis.2020.07.010 |
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