Cargando…

Effects of bacterial lipopolysaccharides on platelet function: inhibition of weak platelet activation

Platelets are anucleate blood cells with reported roles in hemostasis and immune responses, which possess a functional receptor for bacterial lipopolysaccharides (LPSs), the well-known inducers of inflammation. However, LPSs effects on platelets are contradictory. Here we aim to investigate mechanis...

Descripción completa

Detalles Bibliográficos
Autores principales:	Martyanov, Alexey A., Maiorov, Aleksandr S., Filkova, Aleksandra A., Ryabykh, Alexander A., Svidelskaya, Galina S., Artemenko, Elena O., Gambaryan, Stepan P., Panteleev, Mikhail A., Sveshnikova, Anastasia N.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7378070/ https://www.ncbi.nlm.nih.gov/pubmed/32704001 http://dx.doi.org/10.1038/s41598-020-69173-x

Ejemplares similares

Quantitative dynamics of reversible platelet aggregation: mathematical modelling and experiments
por: Filkova, Aleksandra A., et al.
Publicado: (2019)

Development of a Simple Kinetic Mathematical Model of Aggregation of Particles or Clustering of Receptors
por: Garzon Dasgupta, Andrei K., et al.
Publicado: (2020)

Mechanisms of increased mitochondria-dependent necrosis in Wiskott-Aldrich syndrome platelets
por: Obydennyi, Sergey I., et al.
Publicado: (2020)

Platelet functional abnormalities in pediatric patients with kaposiform hemangioendothelioma/Kasabach-Merritt phenomenon
por: Martyanov, Alexey A., et al.
Publicado: (2023)

Platelet Surface-Associated Activation and Secretion-Mediated Inhibition of Coagulation Factor XII
por: Zakharova, Natalia V., et al.
Publicado: (2015)

Platelet Hemostasis Reactions at Different Temperatures Correlate with Intracellular Calcium Concentration
por: Mindukshev, Igor, et al.
Publicado: (2022)

Platelet functional abnormalities and clinical presentation in pediatric patients with germline RUNX1, ANKRD26, and ETV6 mutations
por: Ovsyannikova, Galina S., et al.
Publicado: (2022)

Heterogeneity of Integrin α(IIb)β(3) Function in Pediatric Immune Thrombocytopenia Revealed by Continuous Flow Cytometry Analysis
por: Martyanov, Alexey A., et al.
Publicado: (2020)

Novel hemizygous CORO1A variant leads to combined immunodeficiency with defective platelet calcium signaling and cell mobility
por: Khoreva, Anna, et al.
Publicado: (2023)

Curcumin at Low Doses Potentiates and at High Doses Inhibits ABT-737-Induced Platelet Apoptosis
por: Rukoyatkina, Natalia, et al.
Publicado: (2021)

Longitudinal multiparametric characterization of platelet dysfunction in COVID-19: Effects of disease severity, anticoagulation therapy and inflammatory status
por: Martyanov, Alexey A., et al.
Publicado: (2022)

Platelet function and bleeding at different phases of childhood immune thrombocytopenia
por: Ignatova, Anastasia A., et al.
Publicado: (2021)

Antiplatelet Agents Can Promote Two-Peaked Thrombin Generation in Platelet Rich Plasma: Mechanism and Possible Applications
por: Tarandovskiy, Ivan D., et al.
Publicado: (2013)

Cross-talk of inhibitory and stimulatory signalling pathways of human platelets
por: Walter, Ulrich, et al.
Publicado: (2009)

The Role of NO/sGC/cGMP/PKG Signaling Pathway in Regulation of Platelet Function
por: Gambaryan, Stepan
Publicado: (2022)

Asymmetrical Forces Dictate the Distribution and Morphology of Platelets in Blood Clots
por: Kovalenko, Tatiana A., et al.
Publicado: (2021)

NO inhibits platelet apoptosis by cGMP-dependent and-independent pathways
por: Rukoyatkina, Natalia, et al.
Publicado: (2009)

ML355 Modulates Platelet Activation and Prevents ABT-737 Induced Apoptosis in Platelets
por: Shpakova, Valentina, et al.
Publicado: (2022)

Echicetin Coated Polystyrene Beads: A Novel Tool to Investigate GPIb-Specific Platelet Activation and Aggregation
por: Navdaev, Alexey, et al.
Publicado: (2014)

Differential regulation of platelet inhibition by cGMP- and cAMP-dependent protein kinases
por: Subramanian, Hariharan, et al.
Publicado: (2013)

Feedback Regulation of Syk by Protein Kinase C in Human Platelets
por: Makhoul, Stephanie, et al.
Publicado: (2019)

Nitrous anhydrase activity of carbonic anhydrase II: cysteine is required for nitric oxide (NO) dependent phosphorylation of VASP in human platelets
por: Tsikas, Dimitrios, et al.
Publicado: (2021)

Beyond Hemostasis: Platelet Innate Immune Interactions and Thromboinflammation
por: Mandel, Jonathan, et al.
Publicado: (2022)

Platelet inhibitory effects of the NO independent sGC stimulator riociguat (Bay 63-2561)
por: Reiss, Cora, et al.
Publicado: (2013)

Ex vivo observation of granulocyte activity during thrombus formation
por: Morozova, Daria S., et al.
Publicado: (2022)

Proteomics: A Tool to Study Platelet Function
por: Shevchuk, Olga, et al.
Publicado: (2021)

Effect of ultrapure lipopolysaccharides derived from diverse bacterial species on the modulation of platelet activation
por: Vallance, Thomas M., et al.
Publicado: (2019)

Continuous Modeling of Arterial Platelet Thrombus Formation Using a Spatial Adsorption Equation
por: Babushkina, Evgenia S., et al.
Publicado: (2015)

Hypoxia impairs agonist-induced integrin α(IIb)β(3) activation and platelet aggregation
por: Kiouptsi, Klytaimnistra, et al.
Publicado: (2017)

The human platelet: strong transcriptome correlations among individuals associate weakly with the platelet proteome
por: Londin, Eric R, et al.
Publicado: (2014)

Dual role of the p38 MAPK/cPLA(2) pathway in the regulation of platelet apoptosis induced by ABT-737 and strong platelet agonists
por: Rukoyatkina, N, et al.
Publicado: (2013)

cGMP and cAMP pathways rearrange ARHGAP17 and ARHGEF6 protein complexes to control Rac1 in platelets
por: Nagy, Zoltan, et al.
Publicado: (2015)

EFFECTS OF BACTERIAL ENDOTOXIN ON RABBIT PLATELETS : I. PLATELET AGGREGATION AND RELEASE OF PLATELET FACTORS IN VITRO
por: Des Prez, Roger M., et al.
Publicado: (1961)

Vasodilator-Stimulated Phosphoprotein (VASP)-dependent and -independent pathways regulate thrombin-induced activation of Rap1b in platelets
por: Benz, Peter M., et al.
Publicado: (2016)

Enhancement of platelet response to immune complexes and IgG aggregates by lipid A-rich bacterial lipopolysaccharides
Publicado: (1978)

Platelets, Bacterial Adhesins and the Pneumococcus
por: Jahn, Kristin, et al.
Publicado: (2022)

cAMP- and cGMP-elevating agents inhibit GPIbα-mediated aggregation but not GPIbα-stimulated Syk activation in human platelets
por: Makhoul, Stephanie, et al.
Publicado: (2019)

Erythrocytes do not activate purified and platelet soluble guanylate cyclases even in conditions favourable for NO synthesis
por: Gambaryan, Stepan, et al.
Publicado: (2016)

Platelet factor 4-containing immune complexes induce platelet activation followed by calpain-dependent platelet death
por: Nevzorova, Tatiana A., et al.
Publicado: (2019)

Platelet Counts and Platelet Activation Markers in Obese Subjects
por: Samocha-Bonet, Dorit, et al.
Publicado: (2008)

Cannot write session to /tmp/vufind_sessions/sess_geen63rktaregvdj6bs0b86msi