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Targeting the PLK1-FOXO1 pathway as a novel therapeutic approach for treating advanced prostate cancer
The forkhead box protein O1 (FOXO1) is considered to be a key tumor suppressor due to its involvement in a broad range of cancer-related functions, including cellular differentiation, apoptosis, cell cycle arrest, and DNA damage. Given that inactivation of FOXO1 has been reported in many types of hu...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7378169/ https://www.ncbi.nlm.nih.gov/pubmed/32704044 http://dx.doi.org/10.1038/s41598-020-69338-8 |