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A robust and miniaturized screening platform to study natural products affecting metabolism and survival in Caenorhabditis elegans
In this study a robust, whole organism screening based on Caenorhabditis elegans is presented for the discovery of natural products (NP) with beneficial effects against obesity and age-related diseases. Several parameters of the elaborated workflow were optimized to be adapted for probing multicompo...
Autores principales: | Zwirchmayr, Julia, Kirchweger, Benjamin, Lehner, Theresa, Tahir, Ammar, Pretsch, Dagmar, Rollinger, Judith M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7378205/ https://www.ncbi.nlm.nih.gov/pubmed/32704017 http://dx.doi.org/10.1038/s41598-020-69186-6 |
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