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Reoperations for structurally persistent or recurrent disease after thyroidectomy: analysis via preoperative CT

The incidence rates of structural persistent disease (PD) and recurrent disease (RD) after thyroidectomy, and their clinicoradiological (CT) characteristics, remain poorly understood. Therefore, we characterized differentiated thyroid cancer (DTC) patients who underwent re-operations, with a focus o...

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Autores principales: Kim, Hyeung Kyoo, Ha, Eun Ju, Han, Miran, Lee, Jeonghun, Soh, Euy Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7378257/
https://www.ncbi.nlm.nih.gov/pubmed/32704006
http://dx.doi.org/10.1038/s41598-020-69398-w
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author Kim, Hyeung Kyoo
Ha, Eun Ju
Han, Miran
Lee, Jeonghun
Soh, Euy Young
author_facet Kim, Hyeung Kyoo
Ha, Eun Ju
Han, Miran
Lee, Jeonghun
Soh, Euy Young
author_sort Kim, Hyeung Kyoo
collection PubMed
description The incidence rates of structural persistent disease (PD) and recurrent disease (RD) after thyroidectomy, and their clinicoradiological (CT) characteristics, remain poorly understood. Therefore, we characterized differentiated thyroid cancer (DTC) patients who underwent re-operations, with a focus on preoperative CT scans. We examined neck CT scans obtained prior to initial surgery and reoperation, and classified the disease into four categories according to the persistence/recurrence and neck dissection/non-dissection status. In total, 121 of 9,173 DTC patients underwent reoperations to treat PD or RD; the mean time to reoperation was 25.5 and 54.1 months, respectively. Of all reoperations, 19% (23/121) were performed to treat RD; 81% (98/121) were performed to treat PD. Compared to RD, PD was commonly detected in the non-dissected neck. Tumor multiplicity and the number of pathologically positive lymph nodes were greater in the non-dissected than dissected neck. A review of the CT data revealed more false-negative findings on the 60-s- versus 30–40-s-delay scans of PD patients with non-dissected necks. In conclusion, most of the reoperations performed on DTC patients were for management of PD. Improved preoperative CT assessments and initial surgery, based on the information of clinico-radiological characteristics, are required in the care of DTC patients.
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spelling pubmed-73782572020-07-24 Reoperations for structurally persistent or recurrent disease after thyroidectomy: analysis via preoperative CT Kim, Hyeung Kyoo Ha, Eun Ju Han, Miran Lee, Jeonghun Soh, Euy Young Sci Rep Article The incidence rates of structural persistent disease (PD) and recurrent disease (RD) after thyroidectomy, and their clinicoradiological (CT) characteristics, remain poorly understood. Therefore, we characterized differentiated thyroid cancer (DTC) patients who underwent re-operations, with a focus on preoperative CT scans. We examined neck CT scans obtained prior to initial surgery and reoperation, and classified the disease into four categories according to the persistence/recurrence and neck dissection/non-dissection status. In total, 121 of 9,173 DTC patients underwent reoperations to treat PD or RD; the mean time to reoperation was 25.5 and 54.1 months, respectively. Of all reoperations, 19% (23/121) were performed to treat RD; 81% (98/121) were performed to treat PD. Compared to RD, PD was commonly detected in the non-dissected neck. Tumor multiplicity and the number of pathologically positive lymph nodes were greater in the non-dissected than dissected neck. A review of the CT data revealed more false-negative findings on the 60-s- versus 30–40-s-delay scans of PD patients with non-dissected necks. In conclusion, most of the reoperations performed on DTC patients were for management of PD. Improved preoperative CT assessments and initial surgery, based on the information of clinico-radiological characteristics, are required in the care of DTC patients. Nature Publishing Group UK 2020-07-23 /pmc/articles/PMC7378257/ /pubmed/32704006 http://dx.doi.org/10.1038/s41598-020-69398-w Text en © The Author(s) 2020 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
Kim, Hyeung Kyoo
Ha, Eun Ju
Han, Miran
Lee, Jeonghun
Soh, Euy Young
Reoperations for structurally persistent or recurrent disease after thyroidectomy: analysis via preoperative CT
title Reoperations for structurally persistent or recurrent disease after thyroidectomy: analysis via preoperative CT
title_full Reoperations for structurally persistent or recurrent disease after thyroidectomy: analysis via preoperative CT
title_fullStr Reoperations for structurally persistent or recurrent disease after thyroidectomy: analysis via preoperative CT
title_full_unstemmed Reoperations for structurally persistent or recurrent disease after thyroidectomy: analysis via preoperative CT
title_short Reoperations for structurally persistent or recurrent disease after thyroidectomy: analysis via preoperative CT
title_sort reoperations for structurally persistent or recurrent disease after thyroidectomy: analysis via preoperative ct
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7378257/
https://www.ncbi.nlm.nih.gov/pubmed/32704006
http://dx.doi.org/10.1038/s41598-020-69398-w
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