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Mechanism of Hydrophobic Bile Acid-Induced Hepatocyte Injury and Drug Discovery
Cholestatic liver disease is caused by the obstruction of bile synthesis, transport, and excretion in or outside the liver by a variety of reasons. Long-term persistent cholestasis in the liver can trigger inflammation, necrosis, or apoptosis of hepatocytes. Bile acid nuclear receptors have received...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Frontiers Media S.A.
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7378542/ https://www.ncbi.nlm.nih.gov/pubmed/32765278 http://dx.doi.org/10.3389/fphar.2020.01084 |