Characterization of a novel STAT 2 knock-out hamster model of Crimean-Congo hemorrhagic fever virus pathogenesis

Crimean-Congo hemorrhagic fever virus (CCHFV) is a tick-borne pathogen causing a febrile illness in humans, which can progress to hemorrhagic manifestations, multi-organ failure, and death. Current mouse models of CCHFV infection reliably succumb to virus challenge but vary in their ability to refle...

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Detalles Bibliográficos
Autores principales: Ranadheera, Charlene, Valcourt, Emelissa J., Warner, Bryce M., Poliquin, Guillaume, Rosenke, Kyle, Frost, Kathy, Tierney, Kevin, Saturday, Greg, Miao, Jinxin, Westover, Jonna B., Gowen, Brian B., Booth, Stephanie, Feldmann, Heinz, Wang, Zhongde, Safronetz, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7378551/
https://www.ncbi.nlm.nih.gov/pubmed/32704046
http://dx.doi.org/10.1038/s41598-020-69054-3

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