Polygenic risk and pleiotropy in neurodegenerative diseases

In this paper we explore the phenomenon of pleiotropy in neurodegenerative diseases, focusing on Alzheimer's disease (AD). We summarize the various techniques developed to investigate pleiotropy among traits, elaborating in the polygenic risk scores (PRS) analysis. PRS was designed to assess a...

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Detalles Bibliográficos
Autores principales: Bellou, Eftychia, Stevenson-Hoare, Joshua, Escott-Price, Valentina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academic Press 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7378564/
https://www.ncbi.nlm.nih.gov/pubmed/32445791
http://dx.doi.org/10.1016/j.nbd.2020.104953

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7378564/
https://www.ncbi.nlm.nih.gov/pubmed/32445791
http://dx.doi.org/10.1016/j.nbd.2020.104953

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