Cargando…

Toxicokinetics of 11 Gelsemium Alkaloids in Rats by UPLC-MS/MS

Gelsemium elegans (Gardn. & Champ.) Benth. is a plant belonging to the genus Gelsemium (family Gelsemiaceae), and its main components are alkaloids. It is a Chinese traditional medicinal plant and notoriously known as a highly toxic medicine. However, a method has not yet been found for the simu...

Descripción completa

Detalles Bibliográficos
Autores principales:	Shen, Xiuwei, Ma, Jianshe, Wang, Xianqin, Wen, Congcong, Zhang, Meiling
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7378607/ https://www.ncbi.nlm.nih.gov/pubmed/32733957 http://dx.doi.org/10.1155/2020/8247270

Ejemplares similares

Simultaneous Determination of Six Uncaria Alkaloids in Mouse Blood by UPLC–MS/MS and Its Application in Pharmacokinetics and Bioavailability
por: Chen, Lianguo, et al.
Publicado: (2020)

Pharmacokinetics and UPLC-MS/MS of Delsoline in Mouse Whole Blood
por: Shao, Lingjiu, et al.
Publicado: (2018)

Simultaneous Determination of Ropivacaine and 3-Hydroxy Ropivacaine in Cerebrospinal Fluid by UPLC-MS/MS
por: Chen, Siyuan, et al.
Publicado: (2020)

Determination of Tenacissoside G, Tenacissoside H, and Tenacissoside I in Rat Plasma by UPLC-MS/MS and Their Pharmacokinetics
por: Chen, Fan, et al.
Publicado: (2023)

Quantification of Lappaconitine in Mouse Blood by UPLC-MS/MS and Its Application to a Pharmacokinetic Study
por: Chen, Fan, et al.
Publicado: (2019)

An Efficient UPLC-MS/MS Method for the Determination of Pyrroloquinoline Quinone in Rat Plasma and Its Application to a Toxicokinetic Study
por: Sun, Qingmei, et al.
Publicado: (2022)

Pyrrolizidine alkaloids quantified in soil and water using UPLC-MS/MS
por: Hama, Jawameer R., et al.
Publicado: (2019)

A New UPLC-MS/MS Method Validated for Quantification of Jervine in Rat Plasma and the Study of Its Pharmacokinetics in Rats
por: Chen, Lianguo, et al.
Publicado: (2019)

Determination of tobacco alkaloid enantiomers using reversed phase UPLC/MS/MS
por: Ji, Huihua, et al.
Publicado: (2019)

Development of an LC–MS/MS Assay and Toxicokinetic Characterization of Hexamethylenetetramine in Rats
por: Kim, Woojin, et al.
Publicado: (2023)

Development and Validation of a UPLC-MS/MS Method for the Quantitative Determination and Pharmacokinetic Analysis of Cirsimarin in Rat Plasma
por: Zhang, En, et al.
Publicado: (2021)

Development of UPLC-MS/MS Method for Studying the Pharmacokinetic Interaction Between Dasatinib and Posaconazole in Rats
por: Yang, Suili, et al.
Publicado: (2021)

Pharmacokinetic Study of Delavinone in Mice after Intravenous and Oral Administration by UPLC-MS/MS
por: Wang, Shuanghu, et al.
Publicado: (2019)

Profiling and Pharmacokinetic Studies of Alkaloids in Rats After Oral Administration of Zanthoxylum nitidum Decoction by UPLC-Q-TOF-MS/MS and HPLC-MS/MS
por: Huang, Aihua, et al.
Publicado: (2019)

Pharmacokinetics and metabolism of icaritin in rats by UPLC‐MS/MS
por: Huang, Zhen‐Wu, et al.
Publicado: (2019)

Simultaneous Determination of 32 Pyrrolizidine Alkaloids in Two Traditional Chinese Medicine Preparations by UPLC-MS/MS
por: Cheng, Shi, et al.
Publicado: (2022)

Determination of Gypenoside A and Gypenoside XLIX in Rat Plasma by UPLC-MS/MS and Applied to the Pharmacokinetics and Bioavailability
por: He, Yan, et al.
Publicado: (2022)

Ultra-Liquid Chromatography Tandem Mass Spectrometry (UPLC-MS/MS)-Based Pharmacokinetics and Tissue Distribution Study of Koumine and the Detoxification Mechanism of Glycyrrhiza uralensis Fisch on Gelsemium elegans Benth.
por: Wang, Lin, et al.
Publicado: (2018)

Pharmacokinetic and Metabolism Studies of Curculigoside C by UPLC-MS/MS and UPLC-QTOF-MS
por: Wu, Di, et al.
Publicado: (2018)

Pharmacokinetics of Dibutyl Phthalate (DBP) in the Rat Determined by UPLC-MS/MS
por: Chang, Li-Wen, et al.
Publicado: (2013)

UPLC-MS/MS Profile of Alkaloids with Cytotoxic Properties of Selected Medicinal Plants of the Berberidaceae and Papaveraceae Families
por: Och, Anna, et al.
Publicado: (2017)

Green Extraction-Assisted Pseudo-Targeted Profile of Alkaloids in Lotus Seed Epicarp Based on UPLC-QTOF MS with IDA
por: Cao, Xiaoji, et al.
Publicado: (2022)

Pharmacokinetic and excretion study of three alkaloids in rats using UPLC-MS/MS after oral administration of menispermi rhizoma capsules
por: Yu, Jia, et al.
Publicado: (2018)

Simultaneous Determination and Risk Assessment of Pyrrolizidine Alkaloids in Artemisia capillaris Thunb. by UPLC-MS/MS Together with Chemometrics
por: Chen, Li-Hua, et al.
Publicado: (2019)

Determination of Toxic Pyrrolizidine Alkaloids in Traditional Chinese Herbal Medicines by UPLC-MS/MS and Accompanying Risk Assessment for Human Health
por: Wang, Junchi, et al.
Publicado: (2021)

Enantioseparation and Determination of Penconazole in Rat Plasma by Chiral LC-MS/MS: Application to a Stereoselective Toxicokinetic Study
por: Ma, Siman, et al.
Publicado: (2020)

UPLC-QTOF/MS Analysis of Alkaloids in Traditional Processed Coptis chinensis Franch.
por: Jiang, Xue, et al.
Publicado: (2012)

Simultaneous Determination of 11 Compounds in Gualou Guizhi Granule and Pharmacokinetics Study by UPLC-MS/MS
por: Sun, Chengtao, et al.
Publicado: (2017)

Metabolite Profiling and Distribution of Militarine in Rats Using UPLC-Q-TOF-MS/MS
por: Li, Limin, et al.
Publicado: (2020)

Alkaloids in Erythrina by UPLC-ESI-MS and In Vivo Hypotensive Potential of Extractive Preparations
por: Merlugo, Liara, et al.
Publicado: (2015)

Pharmacokinetic and Metabolism Studies of 12-Riboside-Pseudoginsengenin DQ by UPLC-MS/MS and UPLC-QTOF-MS(E)
por: Wang, Zhenzhou, et al.
Publicado: (2018)

Pharmacokinetics of Herb-Drug Interactions of Plumbagin and Tazemetostat in Rats by UPLC-MS/MS
por: Li, Heng, et al.
Publicado: (2022)

Rapid and Simultaneous Quantification of Five Quinolizidine Alkaloids in Lupinus angustifolius L. and Its Processed Foods by UPLC–MS/MS
por: Hwang, In Min, et al.
Publicado: (2020)

Pharmacokinetic Analysis of Diosgenin in Rat Plasma by a UPLC-MS/MS Approach
por: Liu, Pei, et al.
Publicado: (2022)

Genistein Exposure Interferes with Pharmacokinetics of Celecoxib in SD Male Rats by UPLC-MS/MS
por: Zheng, Xiang, et al.
Publicado: (2017)

Urine metabolomics in rats after administration of ketamine
por: Wen, Congcong, et al.
Publicado: (2015)

Establishment of a sensitive UPLC-MS/MS method to quantify safinamide in rat plasma
por: Wang, Ying, et al.
Publicado: (2023)

Rapid, Validated UPLC-MS/MS Method for Determination of Glibenclamide in Rat Plasma
por: Alam, Mohd Aftab, et al.
Publicado: (2018)

Identification of Sanguinarine Metabolites in Rats Using UPLC-Q-TOF-MS/MS
por: Liu, Mengting, et al.
Publicado: (2023)

Simultaneous determination of cis- and trans-palmitoleic acid in rat serum by UPLC–MS/MS
por: Huang, Wenwen, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_datcalss240ojnauqi2i8hckoa