Longitudinal Pharmacokinetic-Pharmacodynamic Biomarkers Correlate With Treatment Outcome in Drug-Sensitive Pulmonary Tuberculosis: A Population Pharmacokinetic-Pharmacodynamic Analysis

BACKGROUND: This study aims to explore relationships between baseline demographic covariates, plasma antibiotic exposure, sputum bacillary load, and clinical outcome data to help improve future tuberculosis (TB) treatment response predictions. METHODS: Data were available from a longitudinal cohort...

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Detalles Bibliográficos
Autores principales: Kloprogge, Frank, Mwandumba, Henry C, Banda, Gertrude, Kamdolozi, Mercy, Shani, Doris, Corbett, Elizabeth L, Kontogianni, Nadia, Ward, Steve, Khoo, Saye H, Davies, Geraint R, Sloan, Derek J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Major Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7378673/
https://www.ncbi.nlm.nih.gov/pubmed/32733976
http://dx.doi.org/10.1093/ofid/ofaa218

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