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Myeloperoxidase-derived damage to human plasma fibronectin: Modulation by protein binding and thiocyanate ions (SCN(−))

Endothelial cell dysfunction is an early event in cardiovascular disease and atherosclerosis. The origin of this dysfunction is unresolved, but accumulating evidence implicates damaging oxidants, including hypochlorous acid (HOCl), a major oxidant produced by myeloperoxidase (MPO), during chronic in...

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Detalles Bibliográficos
Autores principales: Vanichkitrungruang, Siriluck, Chuang, Christine Y., Hawkins, Clare L., Davies, Michael J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7378696/
https://www.ncbi.nlm.nih.gov/pubmed/32863239
http://dx.doi.org/10.1016/j.redox.2020.101641