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GM-CSF Primes Proinflammatory Monocyte Responses in Ankylosing Spondylitis

Objectives: GM-CSF is a pro-inflammatory cytokine with multiple actions predominantly on myeloid cells. Enhanced GM-CSF expression by lymphocytes from patients with Ankylosing Spondylitis (AS) has recently been described, however, its potential pathogenic role(s) in AS are unknown. Methods: The effe...

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Detalles Bibliográficos
Autores principales: Shi, Hui, Chen, Liye, Ridley, Anna, Zaarour, Nancy, Brough, India, Caucci, Cherilyn, Smith, Julia E., Bowness, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7378736/
https://www.ncbi.nlm.nih.gov/pubmed/32765525
http://dx.doi.org/10.3389/fimmu.2020.01520