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Presence of intrinsically disordered proteins can inhibit the nucleation phase of amyloid fibril formation of Aβ(1–42) in amino acid sequence independent manner

The molecular shield effect was studied for intrinsically disordered proteins (IDPs) that do not adopt compact and stable protein folds. IDPs are found among many stress-responsive gene products and cryoprotective- and drought-protective proteins. We recently reported that some fragments of human ge...

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Detalles Bibliográficos
Autores principales:	Ikeda, Koki, Suzuki, Shota, Shigemitsu, Yoshiki, Tenno, Takeshi, Goda, Natsuko, Oshima, Atsunori, Hiroaki, Hidekazu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7378830/ https://www.ncbi.nlm.nih.gov/pubmed/32703978 http://dx.doi.org/10.1038/s41598-020-69129-1

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