Cargando…

Identification of potential biomarkers for predicting the early onset of diabetic cardiomyopathy in a mouse model

Type 2 diabetes (T2D) is characterized by metabolic derangements that cause a shift in substrate preference, inducing cardiac interstitial fibrosis. Interstitial fibrosis plays a key role in aggravating left ventricular diastolic dysfunction (LVDD), which has previously been associated with the asym...

Descripción completa

Detalles Bibliográficos
Autores principales:	Johnson, Rabia, Nxele, Xolisa, Cour, Martin, Sangweni, Nonhlakanipho, Jooste, Tracey, Hadebe, Nkanyiso, Samodien, Ebrahim, Benjeddou, Mongi, Mazino, Mikateko, Louw, Johan, Lecour, Sandrine
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7378836/ https://www.ncbi.nlm.nih.gov/pubmed/32703998 http://dx.doi.org/10.1038/s41598-020-69254-x

Ejemplares similares

Chronic and moderate consumption of reduced-alcohol wine confers cardiac benefits in a rat model of pulmonary arterial hypertension
por: Diaba-Nuhoho, Patrick, et al.
Publicado: (2021)

Linking LOXL2 to Cardiac Interstitial Fibrosis
por: Erasmus, Melisse, et al.
Publicado: (2020)

Correction to: A Lanosteryl triterpene from Protorhus longifolia augments insulin signaling in type 1 diabetic rats
por: Mabhida, Sihle Ephraim, et al.
Publicado: (2018)

A Lanosteryl triterpene from Protorhus longifolia augments insulin signaling in type 1 diabetic rats
por: Ephraim, Mabhida Sihle, et al.
Publicado: (2018)

Pharmacogenomics of amlodipine and hydrochlorothiazide therapy and the quest for improved control of hypertension: a mini review
por: Johnson, Rabia, et al.
Publicado: (2019)

Doxorubicin-Induced Cardiomyopathy: A Preliminary Study on the Cardioprotective Benefits of 7-Hydroxyflavanone
por: Sangweni, Nonhlakanipho F., et al.
Publicado: (2023)

Diet‐induced DNA methylation within the hypothalamic arcuate nucleus and dysregulated leptin and insulin signaling in the pathophysiology of obesity
por: Samodien, Ebrahim, et al.
Publicado: (2019)

The impact of sugar-sweetened beverage intake on rat cardiac function
por: Driescher, Natasha, et al.
Publicado: (2019)

Diet-induced hypothalamic dysfunction and metabolic disease, and the therapeutic potential of polyphenols
por: Samodien, Ebrahim, et al.
Publicado: (2019)

Molecular insights into the pathophysiology of doxorubicin-induced cardiotoxicity: a graphical representation
por: Sangweni, Nonhlakanipho F., et al.
Publicado: (2022)

The Implication of Low Dose Dimethyl Sulfoxide on Mitochondrial Function and Oxidative Damage in Cultured Cardiac and Cancer Cells
por: Sangweni, Nonhlakanipho F., et al.
Publicado: (2021)

The determination of the effect(s) of solute carrier family 22-member 2 (SLC22A2) haplotype variants on drug binding via molecular dynamic simulation systems
por: Abrahams-October, Zainonesa, et al.
Publicado: (2022)

An In Vitro Study on the Combination Effect of Metformin and N-Acetyl Cysteine against Hyperglycaemia-Induced Cardiac Damage
por: Johnson, Rabia, et al.
Publicado: (2019)

The Prophylactic Effect of Pinocembrin Against Doxorubicin-Induced Cardiotoxicity in an In Vitro H9c2 Cell Model
por: Sangweni, Nonhlakanipho F., et al.
Publicado: (2020)

Prevention of Anthracycline-Induced Cardiotoxicity: The Good and Bad of Current and Alternative Therapies
por: Sangweni, Nonhlakanipho F., et al.
Publicado: (2022)

Sclerocarya birrea (Marula) Extract Inhibits Hepatic Steatosis in db/db Mice
por: Mabasa, Lawrence, et al.
Publicado: (2022)

Cross-sectional study of the association of 5 single nucleotide polymorphisms with enalapril treatment response among South African adults with hypertension
por: Masilela, Charity, et al.
Publicado: (2021)

Socio-demographic and modifiable risk factors of diabetes and hypertension among resource constrained patients from rural areas in Mdantsane Township in South Africa
por: Xhakaza, Lettilia, et al.
Publicado: (2020)

Genetic preservation of SLC22A3 in the Admixed and Xhosa populations living in the Western Cape
por: Pearce, Brendon, et al.
Publicado: (2023)

Prevalence of Hypertension and Its Associated Risk Factors in a Rural Black Population of Mthatha Town, South Africa
por: Sharma, Jyoti Rajan, et al.
Publicado: (2021)

Hypertension in African Populations: Review and Computational Insights
por: Mabhida, Sihle E., et al.
Publicado: (2021)

Reconstruction of major maternal and paternal lineages of the Cape Muslim population
por: Isaacs, Shafieka, et al.
Publicado: (2013)

Prevalence, patterns and determinants of dyslipidaemia among South African adults with comorbidities
por: Masilela, Charity, et al.
Publicado: (2022)

Single Nucleotide Polymorphisms in Amlodipine-Associated Genes and Their Correlation with Blood Pressure Control among South African Adults with Hypertension
por: Masilela, Charity, et al.
Publicado: (2022)

Methylenetetrahydrofolate Reductase Polymorphism (rs1801133) and the Risk of Hypertension among African Populations: A Narrative Synthesis of Literature
por: Mabhida, Sihle E., et al.
Publicado: (2022)

The association of MTHFR (rs1801133) with hypertension in an indigenous south African population
por: Mabhida, Sihle E., et al.
Publicado: (2022)

Genetic polymorphisms and haplotypes of the organic cation transporter 1 gene (SLC22A1) in the Xhosa population of South Africa
por: Jacobs, Clifford, et al.
Publicado: (2014)

Cross-sectional study of prevalence and determinants of uncontrolled hypertension among South African adult residents of Mkhondo municipality
por: Masilela, Charity, et al.
Publicado: (2020)

Single Nucleotide Polymorphisms Associated with Metformin and Sulphonylureas’ Glycaemic Response among South African Adults with Type 2 Diabetes Mellitus
por: Masilela, Charity, et al.
Publicado: (2021)

Genomic Association of Single Nucleotide Polymorphisms with Blood Pressure Response to Hydrochlorothiazide among South African Adults with Hypertension
por: Masilela, Charity, et al.
Publicado: (2020)

Factors associated with glycemic control among South African adult residents of Mkhondo municipality living with diabetes mellitus
por: Masilela, Charity, et al.
Publicado: (2020)

Testicular Dysfunction Ameliorative Effect of the Methanolic Roots Extracts of Maytenus procumbens and Ozoroa paniculosa
por: Cele, Nkosinathi David, et al.
Publicado: (2017)

Corrigendum: Blood-Based DNA Methylation Biomarkers for Type 2 Diabetes: Potential for Clinical Applications
por: Willmer, Tarryn, et al.
Publicado: (2019)

Blood-Based DNA Methylation Biomarkers for Type 2 Diabetes: Potential for Clinical Applications
por: Willmer, Tarryn, et al.
Publicado: (2018)

Crystal Structure and Computational Modeling of the Fab Fragment from a Protective Anti-Ricin Monoclonal Antibody
por: Zhao, Zhiyu, et al.
Publicado: (2012)

Intestinal Barrier Function and Immune Homeostasis Are Missing Links in Obesity and Type 2 Diabetes Development
por: Riedel, Sylvia, et al.
Publicado: (2022)

Cardiovascular Benefits of Dietary Melatonin: A Myth or a Reality?
por: Jiki, Zukiswa, et al.
Publicado: (2018)

Aspalathin Reverts Doxorubicin-Induced Cardiotoxicity through Increased Autophagy and Decreased Expression of p53/mTOR/p62 Signaling
por: Johnson, Rabia, et al.
Publicado: (2017)

Hyperglycemia-induced oxidative stress and heart disease-cardioprotective effects of rooibos flavonoids and phenylpyruvic acid-2-O-β-D-glucoside
por: Dludla, Phiwayinkosi V., et al.
Publicado: (2017)

Influence of Tumour Necrosis Factor Alpha on the Outcome of Ischaemic Postconditioning in the Presence of Obesity and Diabetes
por: Lacerda, Lydia, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_2ev1ekdp3g36jvoekv1lb92l5f