Distinct Single Cell Gene Expression in Peripheral Blood Monocytes Correlates With Tumor Necrosis Factor Inhibitor Treatment Response Groups Defined by Type I Interferon in Rheumatoid Arthritis

Previously, we demonstrated in test and validation cohorts that type I IFN (T1IFN) activity can predict non-response to tumor necrosis factor inhibitors (TNFi) in rheumatoid arthritis (RA). In this study, we examine the biology of non-classical and classical monocytes from RA patients defined by the...

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Detalles Bibliográficos
Autores principales: Wampler Muskardin, Theresa L., Fan, Wei, Jin, Zhongbo, Jensen, Mark A., Dorschner, Jessica M., Ghodke-Puranik, Yogita, Dicke, Betty, Vsetecka, Danielle, Wright, Kerry, Mason, Thomas, Persellin, Scott, Michet, Clement J., Davis, John M., Matteson, Eric, Niewold, Timothy B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7378891/
https://www.ncbi.nlm.nih.gov/pubmed/32765497
http://dx.doi.org/10.3389/fimmu.2020.01384

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