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Evaluation of profibrotic gene transcription in renal tissues from cats with naturally occurring chronic kidney disease

BACKGROUND: Increased gene transcription of hypoxia‐induced mediators of fibrosis in renal tissue has been identified in experimentally induced, ischemic chronic kidney disease (CKD). OBJECTIVE: To characterize hypoxia‐induced profibrotic pathways in naturally occurring CKD in cats. ANIMALS: Twelve...

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Detalles Bibliográficos
Autores principales: Lourenço, Bianca N., Coleman, Amanda E., Tarigo, Jaime L., Berghaus, Roy D., Brown, Cathy A., Rissi, Daniel R., Stanton, James B., Brown, Scott A., Schmiedt, Chad W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7379026/
https://www.ncbi.nlm.nih.gov/pubmed/32468592
http://dx.doi.org/10.1111/jvim.15801

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